A Highly Sensitive Giant Magnetoresistive (GMR) Biosensor Based on the Magnetic Flux Concentrator Effect
Magnetic biosensors have wide applications in biological target detection due to their advantages such as low background noise, convenient detection, and low requirements for sample pretreatment. However, existing magnetic biosensors still have the drawback of low sensitivity compared to optical and...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Micromachines |
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| Online Access: | https://www.mdpi.com/2072-666X/16/5/559 |
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| author | Hao Sun Jiao Li Changhui Zhao Chunming Ren Tian Tian Chong Lei Xuecheng Sun |
| author_facet | Hao Sun Jiao Li Changhui Zhao Chunming Ren Tian Tian Chong Lei Xuecheng Sun |
| author_sort | Hao Sun |
| collection | DOAJ |
| description | Magnetic biosensors have wide applications in biological target detection due to their advantages such as low background noise, convenient detection, and low requirements for sample pretreatment. However, existing magnetic biosensors still have the drawback of low sensitivity compared to optical and electrochemical biosensors. This paper presents the novel design of a high-sensitivity magnetic biosensor by utilizing the magnetic field line convergence effect, which was applied to bacterial detection. The results indicate that it can achieve a detection limitation of 10 CFU/mL, demonstrating that it can be implemented in high-sensitivity biological target detection. |
| format | Article |
| id | doaj-art-761c0ccdea0b4b0da533cb53ec11dc9f |
| institution | DOAJ |
| issn | 2072-666X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj-art-761c0ccdea0b4b0da533cb53ec11dc9f2025-08-20T03:14:46ZengMDPI AGMicromachines2072-666X2025-05-0116555910.3390/mi16050559A Highly Sensitive Giant Magnetoresistive (GMR) Biosensor Based on the Magnetic Flux Concentrator EffectHao Sun0Jiao Li1Changhui Zhao2Chunming Ren3Tian Tian4Chong Lei5Xuecheng Sun6Microelectronics Research & Development Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, ChinaMicroelectronics Research & Development Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, ChinaMicroelectronics Research & Development Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, ChinaMicroelectronics Research & Development Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, ChinaMicroelectronics Research & Development Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, ChinaNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Department of Micro-Nano Electronics, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Dongchuan Road 800, Shanghai 200240, ChinaMicroelectronics Research & Development Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, ChinaMagnetic biosensors have wide applications in biological target detection due to their advantages such as low background noise, convenient detection, and low requirements for sample pretreatment. However, existing magnetic biosensors still have the drawback of low sensitivity compared to optical and electrochemical biosensors. This paper presents the novel design of a high-sensitivity magnetic biosensor by utilizing the magnetic field line convergence effect, which was applied to bacterial detection. The results indicate that it can achieve a detection limitation of 10 CFU/mL, demonstrating that it can be implemented in high-sensitivity biological target detection.https://www.mdpi.com/2072-666X/16/5/559GMR sensorbiosensormagnetic flux concentrator<i>Staphylococcus aureus</i> |
| spellingShingle | Hao Sun Jiao Li Changhui Zhao Chunming Ren Tian Tian Chong Lei Xuecheng Sun A Highly Sensitive Giant Magnetoresistive (GMR) Biosensor Based on the Magnetic Flux Concentrator Effect Micromachines GMR sensor biosensor magnetic flux concentrator <i>Staphylococcus aureus</i> |
| title | A Highly Sensitive Giant Magnetoresistive (GMR) Biosensor Based on the Magnetic Flux Concentrator Effect |
| title_full | A Highly Sensitive Giant Magnetoresistive (GMR) Biosensor Based on the Magnetic Flux Concentrator Effect |
| title_fullStr | A Highly Sensitive Giant Magnetoresistive (GMR) Biosensor Based on the Magnetic Flux Concentrator Effect |
| title_full_unstemmed | A Highly Sensitive Giant Magnetoresistive (GMR) Biosensor Based on the Magnetic Flux Concentrator Effect |
| title_short | A Highly Sensitive Giant Magnetoresistive (GMR) Biosensor Based on the Magnetic Flux Concentrator Effect |
| title_sort | highly sensitive giant magnetoresistive gmr biosensor based on the magnetic flux concentrator effect |
| topic | GMR sensor biosensor magnetic flux concentrator <i>Staphylococcus aureus</i> |
| url | https://www.mdpi.com/2072-666X/16/5/559 |
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