Bacterial TonB-dependent transducers interact with the anti-σ factor in absence of the inducing signal protecting it from proteolysis.

Competitive bacteria like the human pathogen Pseudomonas aeruginosa can acquire iron from different iron carriers, which are usually internalized via outer membrane TonB-dependent receptors (TBDRs). Production of TBDRs is promoted by the presence of the substrate. This regulation often entails a sig...

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Bibliographic Details
Main Authors: Sarah Wettstadt, Francisco J Marcos-Torres, Joaquín R Otero-Asman, Alicia García-Puente, Álvaro Ortega, María A Llamas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002920
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