Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management
Crohn’s disease (CD) is an idiopathic inflammatory bowel disease involving the small and/or large intestine. More than 50% of Western CD patients and up to 88% of Asian CD patients may have small intestinal involvement. Video capsule endoscopy (VCE) has a higher diagnostic yield than small bowel bar...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/8236367 |
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| author | Dong-Hoon Yang Bora Keum Yoon Tae Jeen |
| author_facet | Dong-Hoon Yang Bora Keum Yoon Tae Jeen |
| author_sort | Dong-Hoon Yang |
| collection | DOAJ |
| description | Crohn’s disease (CD) is an idiopathic inflammatory bowel disease involving the small and/or large intestine. More than 50% of Western CD patients and up to 88% of Asian CD patients may have small intestinal involvement. Video capsule endoscopy (VCE) has a higher diagnostic yield than small bowel barium radiography and computed tomography enterography for the detection of small intestinal involvement of CD. VCE also provides diagnostic yields comparable to magnetic resonance- (MR-) based enterography or enteroclysis and may have several advantages over MR-based tests for the detection of early small intestinal lesions. Several studies have suggested the use of VCE-based disease activity scoring systems to evaluate small intestinal mucosal disease activity, although their clinical relevance needs to be further studied. A possible indication for VCE is recurrence monitoring after complete surgical excision of CD-involved segments but its usefulness and efficacy compared with conventional endoscopy should be evaluated. The capsule retention rate ranges from 0 to 5.4% in suspected CD patients and from 0 to 13.2% in established CD patients. If VCE is necessary, significant small bowel stricture should be ruled out before VCE by performing a patency capsule study and/or small bowel radiological study in suspected or established CD patients. |
| format | Article |
| id | doaj-art-7617edd5d5cd41eeaf105fc7b769db18 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-7617edd5d5cd41eeaf105fc7b769db182025-02-03T06:00:51ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/82363678236367Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and ManagementDong-Hoon Yang0Bora Keum1Yoon Tae Jeen2Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of KoreaDepartment of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of KoreaDepartment of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of KoreaCrohn’s disease (CD) is an idiopathic inflammatory bowel disease involving the small and/or large intestine. More than 50% of Western CD patients and up to 88% of Asian CD patients may have small intestinal involvement. Video capsule endoscopy (VCE) has a higher diagnostic yield than small bowel barium radiography and computed tomography enterography for the detection of small intestinal involvement of CD. VCE also provides diagnostic yields comparable to magnetic resonance- (MR-) based enterography or enteroclysis and may have several advantages over MR-based tests for the detection of early small intestinal lesions. Several studies have suggested the use of VCE-based disease activity scoring systems to evaluate small intestinal mucosal disease activity, although their clinical relevance needs to be further studied. A possible indication for VCE is recurrence monitoring after complete surgical excision of CD-involved segments but its usefulness and efficacy compared with conventional endoscopy should be evaluated. The capsule retention rate ranges from 0 to 5.4% in suspected CD patients and from 0 to 13.2% in established CD patients. If VCE is necessary, significant small bowel stricture should be ruled out before VCE by performing a patency capsule study and/or small bowel radiological study in suspected or established CD patients.http://dx.doi.org/10.1155/2016/8236367 |
| spellingShingle | Dong-Hoon Yang Bora Keum Yoon Tae Jeen Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management Gastroenterology Research and Practice |
| title | Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management |
| title_full | Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management |
| title_fullStr | Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management |
| title_full_unstemmed | Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management |
| title_short | Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management |
| title_sort | capsule endoscopy for crohn s disease current status of diagnosis and management |
| url | http://dx.doi.org/10.1155/2016/8236367 |
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