Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamics

BackgroundFrigida (FRI) genes are crucial for regulating flowering time in plants. While the biological importance of the Frigida-like (FRL) gene family has been recognized in Arabidopsis, a systematic analysis of these genes in soybean is lacking. Characterizing FRL genes in soybean will help uncov...

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Main Authors: Song Yu, Yuxuan Wang, Wenwen Ren, Yisheng Fang, Leili Wang, Yifei Zhang, Chengyang Song, Xiao Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Plant Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2025.1536866/full
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author Song Yu
Yuxuan Wang
Yuxuan Wang
Wenwen Ren
Wenwen Ren
Yisheng Fang
Leili Wang
Yifei Zhang
Chengyang Song
Xiao Luo
author_facet Song Yu
Yuxuan Wang
Yuxuan Wang
Wenwen Ren
Wenwen Ren
Yisheng Fang
Leili Wang
Yifei Zhang
Chengyang Song
Xiao Luo
author_sort Song Yu
collection DOAJ
description BackgroundFrigida (FRI) genes are crucial for regulating flowering time in plants. While the biological importance of the Frigida-like (FRL) gene family has been recognized in Arabidopsis, a systematic analysis of these genes in soybean is lacking. Characterizing FRL genes in soybean will help uncover their roles in flowering regulation, offering valuable insights for improving soybean adaptation.ResultsIn this study, we identified 16 Frigida genes in soybean, naming them based on their relationship to the FRL genes in Arabidopsis thaliana. These genes are unevenly distributed across thirteen chromosomes. Phylogenetic analysis categorizes Frigida-like proteins from Arabidopsis, soybean, and rice into four distinct subfamilies (I–IV). Our findings indicate that eight GmFRLs arose from whole-genome duplication (WGD) events, alongside two tandem duplication events. Gene structure analysis confirmed that all GmFRL members contain Frigida domains. Additionally, promoter analysis revealed numerous cis-acting elements related to photoperiodic response, suggesting their significant role in soybean’s light response mechanisms. RNA-seq data demonstrated variable expression levels of GmFRL genes across tissues, including flower, leaf, pod, and seed, and other tissues, while subcellular localization and qPCR analyses further support their vital role in light responsiveness in soybean.ConclusionIn summary, our comprehensive analysis offers valuable insights into the evolution and potential functions of GmFRL genes, emphasizing their significance in photoperiodic responses and establishing a foundation for further research on the GmFRL family.
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spelling doaj-art-7610ac8aaef64de5bac4d1f616cb90202025-08-20T02:58:18ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2025-03-011610.3389/fpls.2025.15368661536866Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamicsSong Yu0Yuxuan Wang1Yuxuan Wang2Wenwen Ren3Wenwen Ren4Yisheng Fang5Leili Wang6Yifei Zhang7Chengyang Song8Xiao Luo9College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang, ChinaCollege of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang, ChinaShandong Key Laboratory of Precision Molecular Crop Design and Breeding, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, ChinaCollege of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang, ChinaShandong Key Laboratory of Precision Molecular Crop Design and Breeding, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, ChinaShandong Key Laboratory of Precision Molecular Crop Design and Breeding, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, ChinaShandong Key Laboratory of Precision Molecular Crop Design and Breeding, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, ChinaCollege of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang, ChinaShandong Key Laboratory of Precision Molecular Crop Design and Breeding, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, ChinaShandong Key Laboratory of Precision Molecular Crop Design and Breeding, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, ChinaBackgroundFrigida (FRI) genes are crucial for regulating flowering time in plants. While the biological importance of the Frigida-like (FRL) gene family has been recognized in Arabidopsis, a systematic analysis of these genes in soybean is lacking. Characterizing FRL genes in soybean will help uncover their roles in flowering regulation, offering valuable insights for improving soybean adaptation.ResultsIn this study, we identified 16 Frigida genes in soybean, naming them based on their relationship to the FRL genes in Arabidopsis thaliana. These genes are unevenly distributed across thirteen chromosomes. Phylogenetic analysis categorizes Frigida-like proteins from Arabidopsis, soybean, and rice into four distinct subfamilies (I–IV). Our findings indicate that eight GmFRLs arose from whole-genome duplication (WGD) events, alongside two tandem duplication events. Gene structure analysis confirmed that all GmFRL members contain Frigida domains. Additionally, promoter analysis revealed numerous cis-acting elements related to photoperiodic response, suggesting their significant role in soybean’s light response mechanisms. RNA-seq data demonstrated variable expression levels of GmFRL genes across tissues, including flower, leaf, pod, and seed, and other tissues, while subcellular localization and qPCR analyses further support their vital role in light responsiveness in soybean.ConclusionIn summary, our comprehensive analysis offers valuable insights into the evolution and potential functions of GmFRL genes, emphasizing their significance in photoperiodic responses and establishing a foundation for further research on the GmFRL family.https://www.frontiersin.org/articles/10.3389/fpls.2025.1536866/fullGlycine maxFRIGIDA-LIKEphotoperiod responsegene expressiongenome-wide identification
spellingShingle Song Yu
Yuxuan Wang
Yuxuan Wang
Wenwen Ren
Wenwen Ren
Yisheng Fang
Leili Wang
Yifei Zhang
Chengyang Song
Xiao Luo
Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamics
Frontiers in Plant Science
Glycine max
FRIGIDA-LIKE
photoperiod response
gene expression
genome-wide identification
title Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamics
title_full Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamics
title_fullStr Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamics
title_full_unstemmed Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamics
title_short Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamics
title_sort comprehensive genome wide analysis of the gmfrigida gene family in soybean identification characterization and expression dynamics
topic Glycine max
FRIGIDA-LIKE
photoperiod response
gene expression
genome-wide identification
url https://www.frontiersin.org/articles/10.3389/fpls.2025.1536866/full
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