Laser Microinterferometry for API Solubility and Phase Equilibria: Darunavir as a Case Example

Laser Microinterferometry for API Solubility and Phase Equilibria: Darunavir as a Case Example

<b>Background:</b> The solubility and phase behavior of APIs are crucial for the development of medicines and ensuring their stability. However, conventional experimental approaches often do not allow for the precise determination of phase transitions and solubility limits, especially fo...

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Bibliographic Details
Main Authors: Veronika Makarova, Mark Mandrik, Sergey Antonov
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceutics
Subjects:
thermodynamic solubility
phase diagrams
laser microinterferometry
dissolution kinetics
active pharmaceutical ingredient
early-stage drug development
Online Access:https://www.mdpi.com/1999-4923/17/7/875
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