Seronegative Disseminated Cryptococcosis: A Case Report
Cryptococcal infection is a major cause of morbidity and mortality in immunocompromised patients, especially those with HIV/AIDS. The cryptococcal antigen (CrAg) lateral flow assay (LFA) has become an essential diagnostic tool due to its high sensitivity, specificity, and ability to produce rapid re...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/carm/5564622 |
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| _version_ | 1850177775551381504 |
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| author | Maria Roell Kevin Baker |
| author_facet | Maria Roell Kevin Baker |
| author_sort | Maria Roell |
| collection | DOAJ |
| description | Cryptococcal infection is a major cause of morbidity and mortality in immunocompromised patients, especially those with HIV/AIDS. The cryptococcal antigen (CrAg) lateral flow assay (LFA) has become an essential diagnostic tool due to its high sensitivity, specificity, and ability to produce rapid results. However, this test is not without limitations. This case details a patient with disseminated cryptococcosis with a negative serum CrAg LFA and an unremarkable brain MRI to demonstrate the importance of cerebrospinal fluid testing in high-risk immunocompromised individuals. |
| format | Article |
| id | doaj-art-75dd4bb184794d43822b8f936df0dad1 |
| institution | OA Journals |
| issn | 1687-9635 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-75dd4bb184794d43822b8f936df0dad12025-08-20T02:18:55ZengWileyCase Reports in Medicine1687-96352025-01-01202510.1155/carm/5564622Seronegative Disseminated Cryptococcosis: A Case ReportMaria Roell0Kevin Baker1Department of Internal MedicineDepartment of Internal MedicineCryptococcal infection is a major cause of morbidity and mortality in immunocompromised patients, especially those with HIV/AIDS. The cryptococcal antigen (CrAg) lateral flow assay (LFA) has become an essential diagnostic tool due to its high sensitivity, specificity, and ability to produce rapid results. However, this test is not without limitations. This case details a patient with disseminated cryptococcosis with a negative serum CrAg LFA and an unremarkable brain MRI to demonstrate the importance of cerebrospinal fluid testing in high-risk immunocompromised individuals.http://dx.doi.org/10.1155/carm/5564622 |
| spellingShingle | Maria Roell Kevin Baker Seronegative Disseminated Cryptococcosis: A Case Report Case Reports in Medicine |
| title | Seronegative Disseminated Cryptococcosis: A Case Report |
| title_full | Seronegative Disseminated Cryptococcosis: A Case Report |
| title_fullStr | Seronegative Disseminated Cryptococcosis: A Case Report |
| title_full_unstemmed | Seronegative Disseminated Cryptococcosis: A Case Report |
| title_short | Seronegative Disseminated Cryptococcosis: A Case Report |
| title_sort | seronegative disseminated cryptococcosis a case report |
| url | http://dx.doi.org/10.1155/carm/5564622 |
| work_keys_str_mv | AT mariaroell seronegativedisseminatedcryptococcosisacasereport AT kevinbaker seronegativedisseminatedcryptococcosisacasereport |