An intrinsic connection between COVID-19 and aging

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a rapidly spreading outbreak of coronavirus disease 2019 (the COVID-19 pandemic). COVID-19 has severely affected healthcare systems worldwide, as well as the global economy, and has significantly increased morbidity and mortality ra...

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Main Authors: Jingchao Wang, Jonathan Wei, Fabin Dang, Hiroyuki Inuzuka
Format: Article
Language:English
Published: Compuscript Ltd 2023-08-01
Series:Acta Materia Medica
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0030
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author Jingchao Wang
Jonathan Wei
Fabin Dang
Hiroyuki Inuzuka
author_facet Jingchao Wang
Jonathan Wei
Fabin Dang
Hiroyuki Inuzuka
author_sort Jingchao Wang
collection DOAJ
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a rapidly spreading outbreak of coronavirus disease 2019 (the COVID-19 pandemic). COVID-19 has severely affected healthcare systems worldwide, as well as the global economy, and has significantly increased morbidity and mortality rates. The majority of COVID-19-related deaths occurred in older individuals, primarily among those with concomitant diseases, including metabolic, respiratory, and cardiovascular diseases. Aging hallmarks, such as cellular senescence, chronic inflammation, and genomic instability, partially explain the increased disease severity at the molecular level with advancing age. Other multifactorial considerations, including healthcare facilities, socioeconomic status, and dissemination of epidemic information, may help control morbidity in the elderly population. While the World Health Organization declared an end to the emergency status of COVID-19 in May 2023, physical and emotional impairments may persist after recovery from the virus. Precautions should therefore be taken to prevent future pandemics, and suitable emphasis should be placed on addressing persistent COVID-19 and preventing future pandemics.
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institution Kabale University
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spelling doaj-art-75d9dec177524a5ab76418d7d92a9ec62025-08-20T03:31:53ZengCompuscript LtdActa Materia Medica2737-79462023-08-012334234610.15212/AMM-2023-0030An intrinsic connection between COVID-19 and agingJingchao WangJonathan WeiFabin DangHiroyuki InuzukaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a rapidly spreading outbreak of coronavirus disease 2019 (the COVID-19 pandemic). COVID-19 has severely affected healthcare systems worldwide, as well as the global economy, and has significantly increased morbidity and mortality rates. The majority of COVID-19-related deaths occurred in older individuals, primarily among those with concomitant diseases, including metabolic, respiratory, and cardiovascular diseases. Aging hallmarks, such as cellular senescence, chronic inflammation, and genomic instability, partially explain the increased disease severity at the molecular level with advancing age. Other multifactorial considerations, including healthcare facilities, socioeconomic status, and dissemination of epidemic information, may help control morbidity in the elderly population. While the World Health Organization declared an end to the emergency status of COVID-19 in May 2023, physical and emotional impairments may persist after recovery from the virus. Precautions should therefore be taken to prevent future pandemics, and suitable emphasis should be placed on addressing persistent COVID-19 and preventing future pandemics.https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0030
spellingShingle Jingchao Wang
Jonathan Wei
Fabin Dang
Hiroyuki Inuzuka
An intrinsic connection between COVID-19 and aging
Acta Materia Medica
title An intrinsic connection between COVID-19 and aging
title_full An intrinsic connection between COVID-19 and aging
title_fullStr An intrinsic connection between COVID-19 and aging
title_full_unstemmed An intrinsic connection between COVID-19 and aging
title_short An intrinsic connection between COVID-19 and aging
title_sort intrinsic connection between covid 19 and aging
url https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0030
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