Does hemodialysis ultrafiltration mainly affect the extracellular fluid

Objective To investigate the effects of hemodialysis on intracellular and extracellular fluid space.Methods Sixty-eight stable maintenance hemodialysis(MHD) patients were selected in Air Force General Hospital of PLA from March 1,2012 to December 31,2014.The whole body multiple frequency bioelectric...

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Main Authors: ZHANG Lei, LI Xin-lun, GAO Zhuo, QIU De-jun, LIU Jing-min, ZHENG Xiu-yuan, LUN LI-de
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2016-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57918830&Fpath=home&index=0
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author ZHANG Lei
LI Xin-lun
GAO Zhuo
QIU De-jun
LIU Jing-min
ZHENG Xiu-yuan
LUN LI-de
author_facet ZHANG Lei
LI Xin-lun
GAO Zhuo
QIU De-jun
LIU Jing-min
ZHENG Xiu-yuan
LUN LI-de
author_sort ZHANG Lei
collection DOAJ
description Objective To investigate the effects of hemodialysis on intracellular and extracellular fluid space.Methods Sixty-eight stable maintenance hemodialysis(MHD) patients were selected in Air Force General Hospital of PLA from March 1,2012 to December 31,2014.The whole body multiple frequency bioelectrical impedance was used to measure the volume of intracellular water(ICW)and extracellular water(ECW) before and one min after dialysis,and the volume of ICW and ECW reduction after hemodialysis treatment(△ICW and △ECW).The effect of dialysis ultrafiltration on dehydration rate of ICW and ECW(△ICW/ICW and △ECW/ECW) was observed Results The ICW was decreased from(23.34±4.53)kg to(21.64±4.18) kg 0 = 9.518,P<0.01)) △ICW=(1.70±1.47)kg,and ECW was decreased from(12.02 ± 2.41) kg to(10.91 ± 2.20) kg(t = 10.726,P<0.01),AECW= CI.11 ± 0.85) kg before and after dialysis.The changes of two kinds of fluid rate were AICW/ICW=(7.07%±5A%) and △ECW/ECW =(9.02%± 5.80%).The ratio of ICW/ECW was 1.99:1 after dialysis,which was highly consistent with the results measured by gold standard of applying isotope labeling(2.0=1) and superior to 1.11:1 in most other studies.Conclusions Hemodialysis ultrafiltration volume is simultaneously derived from both intracellular and extracellular space,not mainly the extracellular space.This method is probably the most close to the gold standard method.
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issn 1671-2390
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spelling doaj-art-75d5ca605f294eae9007bea2fafc324e2025-08-20T03:48:58ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902016-01-01404357918830Does hemodialysis ultrafiltration mainly affect the extracellular fluidZHANG LeiLI Xin-lunGAO ZhuoQIU De-junLIU Jing-minZHENG Xiu-yuanLUN LI-deObjective To investigate the effects of hemodialysis on intracellular and extracellular fluid space.Methods Sixty-eight stable maintenance hemodialysis(MHD) patients were selected in Air Force General Hospital of PLA from March 1,2012 to December 31,2014.The whole body multiple frequency bioelectrical impedance was used to measure the volume of intracellular water(ICW)and extracellular water(ECW) before and one min after dialysis,and the volume of ICW and ECW reduction after hemodialysis treatment(△ICW and △ECW).The effect of dialysis ultrafiltration on dehydration rate of ICW and ECW(△ICW/ICW and △ECW/ECW) was observed Results The ICW was decreased from(23.34±4.53)kg to(21.64±4.18) kg 0 = 9.518,P<0.01)) △ICW=(1.70±1.47)kg,and ECW was decreased from(12.02 ± 2.41) kg to(10.91 ± 2.20) kg(t = 10.726,P<0.01),AECW= CI.11 ± 0.85) kg before and after dialysis.The changes of two kinds of fluid rate were AICW/ICW=(7.07%±5A%) and △ECW/ECW =(9.02%± 5.80%).The ratio of ICW/ECW was 1.99:1 after dialysis,which was highly consistent with the results measured by gold standard of applying isotope labeling(2.0=1) and superior to 1.11:1 in most other studies.Conclusions Hemodialysis ultrafiltration volume is simultaneously derived from both intracellular and extracellular space,not mainly the extracellular space.This method is probably the most close to the gold standard method.http://www.lcszb.com/thesisDetails?columnId=57918830&Fpath=home&index=0Intracellular fluidExtracellular fluidHemodialysisUltrafiltration
spellingShingle ZHANG Lei
LI Xin-lun
GAO Zhuo
QIU De-jun
LIU Jing-min
ZHENG Xiu-yuan
LUN LI-de
Does hemodialysis ultrafiltration mainly affect the extracellular fluid
Linchuang shenzangbing zazhi
Intracellular fluid
Extracellular fluid
Hemodialysis
Ultrafiltration
title Does hemodialysis ultrafiltration mainly affect the extracellular fluid
title_full Does hemodialysis ultrafiltration mainly affect the extracellular fluid
title_fullStr Does hemodialysis ultrafiltration mainly affect the extracellular fluid
title_full_unstemmed Does hemodialysis ultrafiltration mainly affect the extracellular fluid
title_short Does hemodialysis ultrafiltration mainly affect the extracellular fluid
title_sort does hemodialysis ultrafiltration mainly affect the extracellular fluid
topic Intracellular fluid
Extracellular fluid
Hemodialysis
Ultrafiltration
url http://www.lcszb.com/thesisDetails?columnId=57918830&Fpath=home&index=0
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AT qiudejun doeshemodialysisultrafiltrationmainlyaffecttheextracellularfluid
AT liujingmin doeshemodialysisultrafiltrationmainlyaffecttheextracellularfluid
AT zhengxiuyuan doeshemodialysisultrafiltrationmainlyaffecttheextracellularfluid
AT lunlide doeshemodialysisultrafiltrationmainlyaffecttheextracellularfluid