Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive Keratograph

Purpose. This study aims to evaluate dry eye and ocular surface conditions of myopic teenagers by using questionnaire and clinical examinations. Methods. A total of 496 eyes from 248 myopic teenagers (7–18 years old) were studied. We administered Ocular Surface Disease Index (OSDI) questionnaire, sl...

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Main Authors: Xiu Wang, Xiaoxiao Lu, Jun Yang, Ruihua Wei, Liyuan Yang, Shaozhen Zhao, Xilian Wang
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2016/6761206
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author Xiu Wang
Xiaoxiao Lu
Jun Yang
Ruihua Wei
Liyuan Yang
Shaozhen Zhao
Xilian Wang
author_facet Xiu Wang
Xiaoxiao Lu
Jun Yang
Ruihua Wei
Liyuan Yang
Shaozhen Zhao
Xilian Wang
author_sort Xiu Wang
collection DOAJ
description Purpose. This study aims to evaluate dry eye and ocular surface conditions of myopic teenagers by using questionnaire and clinical examinations. Methods. A total of 496 eyes from 248 myopic teenagers (7–18 years old) were studied. We administered Ocular Surface Disease Index (OSDI) questionnaire, slit-lamp examination, and Keratograph 5M. The patients were divided into 2 groups based on OSDI dry eye standard, and their ocular surfaces and meibomian gland conditions were evaluated. Results. The tear meniscus heights of the dry eye and normal groups were in normal range. Corneal fluorescein scores were significantly higher whereas noninvasive break-up time was dramatically shorter in the dry eye group than in the normal group. All three meibomian gland dysfunction parameters (i.e., meibomian gland orifice scores, meibomian gland secretion scores, and meibomian gland dropout scores) of the dry eye group were significantly higher than those of the normal group (P<0.0001). Conclusions. The prevalence of dry eye in myopic teenagers is 18.95%. Meibomian gland dysfunction plays an important role in dry eye in myopic teenagers. The Keratograph 5M appears to provide an effective noninvasive method for assessing ocular surface situation of myopic teenagers.
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spelling doaj-art-75d1cd6b4abc44b1b18f59b7a1d6e02a2025-02-03T01:11:14ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/67612066761206Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive KeratographXiu Wang0Xiaoxiao Lu1Jun Yang2Ruihua Wei3Liyuan Yang4Shaozhen Zhao5Xilian Wang6Tianjin Medical University Eye Hospital, Fukang Road No. 251, Nankai District, Tianjin 300384, ChinaTianjin Medical University Eye Hospital, Fukang Road No. 251, Nankai District, Tianjin 300384, ChinaTianjin Medical University Eye Hospital, Fukang Road No. 251, Nankai District, Tianjin 300384, ChinaTianjin Medical University Eye Hospital, Fukang Road No. 251, Nankai District, Tianjin 300384, ChinaTianjin Medical University Eye Hospital, Fukang Road No. 251, Nankai District, Tianjin 300384, ChinaTianjin Medical University Eye Hospital, Fukang Road No. 251, Nankai District, Tianjin 300384, ChinaTianjin Beichen Hospital, Beiyi Road No. 7, Beichen District, Tianjin 300400, ChinaPurpose. This study aims to evaluate dry eye and ocular surface conditions of myopic teenagers by using questionnaire and clinical examinations. Methods. A total of 496 eyes from 248 myopic teenagers (7–18 years old) were studied. We administered Ocular Surface Disease Index (OSDI) questionnaire, slit-lamp examination, and Keratograph 5M. The patients were divided into 2 groups based on OSDI dry eye standard, and their ocular surfaces and meibomian gland conditions were evaluated. Results. The tear meniscus heights of the dry eye and normal groups were in normal range. Corneal fluorescein scores were significantly higher whereas noninvasive break-up time was dramatically shorter in the dry eye group than in the normal group. All three meibomian gland dysfunction parameters (i.e., meibomian gland orifice scores, meibomian gland secretion scores, and meibomian gland dropout scores) of the dry eye group were significantly higher than those of the normal group (P<0.0001). Conclusions. The prevalence of dry eye in myopic teenagers is 18.95%. Meibomian gland dysfunction plays an important role in dry eye in myopic teenagers. The Keratograph 5M appears to provide an effective noninvasive method for assessing ocular surface situation of myopic teenagers.http://dx.doi.org/10.1155/2016/6761206
spellingShingle Xiu Wang
Xiaoxiao Lu
Jun Yang
Ruihua Wei
Liyuan Yang
Shaozhen Zhao
Xilian Wang
Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive Keratograph
Journal of Ophthalmology
title Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive Keratograph
title_full Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive Keratograph
title_fullStr Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive Keratograph
title_full_unstemmed Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive Keratograph
title_short Evaluation of Dry Eye and Meibomian Gland Dysfunction in Teenagers with Myopia through Noninvasive Keratograph
title_sort evaluation of dry eye and meibomian gland dysfunction in teenagers with myopia through noninvasive keratograph
url http://dx.doi.org/10.1155/2016/6761206
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