ZmBARK1 as a low-temperature tolerance gene in maize germination

Maize (Zea mays L.), a globally significant cereal crop, is produced in vast quantities worldwide. However, its growth is severely constrained by low temperatures, particularly during seed germination, which significantly impairs seedling emergence. In this study, genetic diversity across six germin...

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Main Authors: Qingyu Xu, Yiying Song, Di Bao, Lingzhi Meng, Hong Di, Lin Zhang, Ling Dong, Xing Zeng, Jiayue Zhang, Chunxiang Li, Jiapeng Xing, Naifu Zhang, Xin Li, Jianfeng Weng, Zhenhua Wang, Yu Zhou
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-08-01
Series:Crop Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214514125001114
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author Qingyu Xu
Yiying Song
Di Bao
Lingzhi Meng
Hong Di
Lin Zhang
Ling Dong
Xing Zeng
Jiayue Zhang
Chunxiang Li
Jiapeng Xing
Naifu Zhang
Xin Li
Jianfeng Weng
Zhenhua Wang
Yu Zhou
author_facet Qingyu Xu
Yiying Song
Di Bao
Lingzhi Meng
Hong Di
Lin Zhang
Ling Dong
Xing Zeng
Jiayue Zhang
Chunxiang Li
Jiapeng Xing
Naifu Zhang
Xin Li
Jianfeng Weng
Zhenhua Wang
Yu Zhou
author_sort Qingyu Xu
collection DOAJ
description Maize (Zea mays L.), a globally significant cereal crop, is produced in vast quantities worldwide. However, its growth is severely constrained by low temperatures, particularly during seed germination, which significantly impairs seedling emergence. In this study, genetic diversity across six germination-associated phenotypic traits (RGR, RSL, RTL, RRSA, RRV, and RSVI) of 304 inbred lines was analyzed, to evaluate the capacity of these lines for low-temperature tolerance. Genome-wide association study (GWAS) was carried out by combining six germination-associated phenotypic traits and genotypic data from 30-fold resequencing. The gene ZmBARK1 was identified through integrated GWAS and RNA-seq analyses, and its association with low-temperature tolerance during maize germination was validated by quantitative real-time PCR (qRT-PCR). ZmBARK1, encoding BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1, was located on the bin 4.09 region of maize chromosome 4. Amino acid comparison and subcellular localization analyses revealed that ZmBARK1 is highly homologous to AtBAK1 and is localized to the plasma membrane of the cell, which may be involved in regulating brassinosteroid (BR) signaling. In addition, we revealed the role of ZmBARK1 in low-temperature tolerance during maize germination. Compared with wild-type (WT), the ethyl methanesulfonate (EMS) mutant zmbark1 was characterized by substantially enhanced low-temperature tolerance. Overall, these findings provide promising candidate genes, improve low-temperature tolerance in maize, and advance the understanding of regulatory mechanisms underlying maize’s response to low-temperature stress.
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spelling doaj-art-75d056721cbf4fca85df16b52d4c34e92025-08-22T04:56:28ZengKeAi Communications Co., Ltd.Crop Journal2214-51412025-08-011341197120910.1016/j.cj.2025.04.012ZmBARK1 as a low-temperature tolerance gene in maize germinationQingyu Xu0Yiying Song1Di Bao2Lingzhi Meng3Hong Di4Lin Zhang5Ling Dong6Xing Zeng7Jiayue Zhang8Chunxiang Li9Jiapeng Xing10Naifu Zhang11Xin Li12Jianfeng Weng13Zhenhua Wang14Yu Zhou15Key Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaCollege of Agriculture and Biology of Liaocheng University, Liaocheng 252000, Shandong, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaKey Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, ChinaState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China; Corresponding authors.Key Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, China; Corresponding authors.Key Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Engineering Technology Research Center of Maize Germplasm Resources Innovation on Cold land of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, Heilongjiang, China; Corresponding authors.Maize (Zea mays L.), a globally significant cereal crop, is produced in vast quantities worldwide. However, its growth is severely constrained by low temperatures, particularly during seed germination, which significantly impairs seedling emergence. In this study, genetic diversity across six germination-associated phenotypic traits (RGR, RSL, RTL, RRSA, RRV, and RSVI) of 304 inbred lines was analyzed, to evaluate the capacity of these lines for low-temperature tolerance. Genome-wide association study (GWAS) was carried out by combining six germination-associated phenotypic traits and genotypic data from 30-fold resequencing. The gene ZmBARK1 was identified through integrated GWAS and RNA-seq analyses, and its association with low-temperature tolerance during maize germination was validated by quantitative real-time PCR (qRT-PCR). ZmBARK1, encoding BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1, was located on the bin 4.09 region of maize chromosome 4. Amino acid comparison and subcellular localization analyses revealed that ZmBARK1 is highly homologous to AtBAK1 and is localized to the plasma membrane of the cell, which may be involved in regulating brassinosteroid (BR) signaling. In addition, we revealed the role of ZmBARK1 in low-temperature tolerance during maize germination. Compared with wild-type (WT), the ethyl methanesulfonate (EMS) mutant zmbark1 was characterized by substantially enhanced low-temperature tolerance. Overall, these findings provide promising candidate genes, improve low-temperature tolerance in maize, and advance the understanding of regulatory mechanisms underlying maize’s response to low-temperature stress.http://www.sciencedirect.com/science/article/pii/S2214514125001114MaizeLow-temperatureGWASRNA-seqZmBARK1
spellingShingle Qingyu Xu
Yiying Song
Di Bao
Lingzhi Meng
Hong Di
Lin Zhang
Ling Dong
Xing Zeng
Jiayue Zhang
Chunxiang Li
Jiapeng Xing
Naifu Zhang
Xin Li
Jianfeng Weng
Zhenhua Wang
Yu Zhou
ZmBARK1 as a low-temperature tolerance gene in maize germination
Crop Journal
Maize
Low-temperature
GWAS
RNA-seq
ZmBARK1
title ZmBARK1 as a low-temperature tolerance gene in maize germination
title_full ZmBARK1 as a low-temperature tolerance gene in maize germination
title_fullStr ZmBARK1 as a low-temperature tolerance gene in maize germination
title_full_unstemmed ZmBARK1 as a low-temperature tolerance gene in maize germination
title_short ZmBARK1 as a low-temperature tolerance gene in maize germination
title_sort zmbark1 as a low temperature tolerance gene in maize germination
topic Maize
Low-temperature
GWAS
RNA-seq
ZmBARK1
url http://www.sciencedirect.com/science/article/pii/S2214514125001114
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