Outcome of Endoscopic Ultrasound-Guided Sampling of Mediastinal Lymphadenopathy

Background and Objectives. Endoscopic ultrasound (EUS)- guided transesophageal fine needle biopsy has been used as a method for histologic evaluation of mediastinal lymph nodes (LNs). This study aimed to compare the outcomes of the EUS-guided sampling with mediastinal lymphadenopathy using a 19-gaug...

Full description

Saved in:
Bibliographic Details
Main Authors: Tae Young Park, Jeong Seop Moon
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2022/4486241
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832549583840870400
author Tae Young Park
Jeong Seop Moon
author_facet Tae Young Park
Jeong Seop Moon
author_sort Tae Young Park
collection DOAJ
description Background and Objectives. Endoscopic ultrasound (EUS)- guided transesophageal fine needle biopsy has been used as a method for histologic evaluation of mediastinal lymph nodes (LNs). This study aimed to compare the outcomes of the EUS-guided sampling with mediastinal lymphadenopathy using a 19-gauge trucut needle and 22-gauge fine needle aspiration (FNA) needle. Methods. From May 2006 to January 2017, patients with mediastinal lymphadenopathy, who received an EUS-guided trucut biopsy or an FNA biopsy, were retrospectively reviewed. Demographic data, endosonographic characteristics of LNs including size, shape, border, echotexture, and echogenicity, diagnostic yield, and adverse events between the trucut needle group and aspiration needle group were compared. Results. A total of 69 patients (trucut group, n=33 vs. aspiration group, n=36) were identified. There were no significant differences in demographic data, indication for an EUS-guided biopsy, location of LNs, number of needle passes, and endosonographic features of LNs between the two groups. The sizes of LNs were larger in the trucut group than in the aspiration group (28.9±14.0 mm vs. 21.1±8.8 mm, P=0.007). However, there was no significant difference in the ratio of LNs that were ≥10 mm in both groups. The overall accuracy of the EUS-guided biopsy for the diagnosis of malignant lesions was 79.7% (55/69). There were no significant differences in the histological diagnostic yield of malignant LNs between the two groups. There were no significant procedure-related adverse events in both groups. Conclusion. The EUS-guided biopsy can be a useful method for histologic evaluation of mediastinal nodal lesions.
format Article
id doaj-art-75cd5949e2264add8f26253055461ff5
institution Kabale University
issn 1687-630X
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Gastroenterology Research and Practice
spelling doaj-art-75cd5949e2264add8f26253055461ff52025-02-03T06:10:55ZengWileyGastroenterology Research and Practice1687-630X2022-01-01202210.1155/2022/4486241Outcome of Endoscopic Ultrasound-Guided Sampling of Mediastinal LymphadenopathyTae Young Park0Jeong Seop Moon1Division of GastroenterologyDepartment of Internal MedicineBackground and Objectives. Endoscopic ultrasound (EUS)- guided transesophageal fine needle biopsy has been used as a method for histologic evaluation of mediastinal lymph nodes (LNs). This study aimed to compare the outcomes of the EUS-guided sampling with mediastinal lymphadenopathy using a 19-gauge trucut needle and 22-gauge fine needle aspiration (FNA) needle. Methods. From May 2006 to January 2017, patients with mediastinal lymphadenopathy, who received an EUS-guided trucut biopsy or an FNA biopsy, were retrospectively reviewed. Demographic data, endosonographic characteristics of LNs including size, shape, border, echotexture, and echogenicity, diagnostic yield, and adverse events between the trucut needle group and aspiration needle group were compared. Results. A total of 69 patients (trucut group, n=33 vs. aspiration group, n=36) were identified. There were no significant differences in demographic data, indication for an EUS-guided biopsy, location of LNs, number of needle passes, and endosonographic features of LNs between the two groups. The sizes of LNs were larger in the trucut group than in the aspiration group (28.9±14.0 mm vs. 21.1±8.8 mm, P=0.007). However, there was no significant difference in the ratio of LNs that were ≥10 mm in both groups. The overall accuracy of the EUS-guided biopsy for the diagnosis of malignant lesions was 79.7% (55/69). There were no significant differences in the histological diagnostic yield of malignant LNs between the two groups. There were no significant procedure-related adverse events in both groups. Conclusion. The EUS-guided biopsy can be a useful method for histologic evaluation of mediastinal nodal lesions.http://dx.doi.org/10.1155/2022/4486241
spellingShingle Tae Young Park
Jeong Seop Moon
Outcome of Endoscopic Ultrasound-Guided Sampling of Mediastinal Lymphadenopathy
Gastroenterology Research and Practice
title Outcome of Endoscopic Ultrasound-Guided Sampling of Mediastinal Lymphadenopathy
title_full Outcome of Endoscopic Ultrasound-Guided Sampling of Mediastinal Lymphadenopathy
title_fullStr Outcome of Endoscopic Ultrasound-Guided Sampling of Mediastinal Lymphadenopathy
title_full_unstemmed Outcome of Endoscopic Ultrasound-Guided Sampling of Mediastinal Lymphadenopathy
title_short Outcome of Endoscopic Ultrasound-Guided Sampling of Mediastinal Lymphadenopathy
title_sort outcome of endoscopic ultrasound guided sampling of mediastinal lymphadenopathy
url http://dx.doi.org/10.1155/2022/4486241
work_keys_str_mv AT taeyoungpark outcomeofendoscopicultrasoundguidedsamplingofmediastinallymphadenopathy
AT jeongseopmoon outcomeofendoscopicultrasoundguidedsamplingofmediastinallymphadenopathy