Left ventricular noncompaction in a patient presenting with a left ventricular failure

Introduction. Left ventricular noncompaction (LVNC) is a congenital disorder characterised by prominent trabeculations in the left ventricular myocardium. This heart condition very often goes completely undetected, or is mistaken for hypertrophic cardiomyopathy or coronary disease. Case report. A mi...

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Main Authors: Ristić-Anđelkov Anđelka, Vraneš Danijela, Mladenović Zorica, Rusović Siniša, Ratković Nenad, Vukotić Snježana, Torbica Lidija, Milić Veljko, Mišić Tatjana, Ristić Mirjana, Baškot Branislav, Pandrc Milena
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2018-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600354R.pdf
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author Ristić-Anđelkov Anđelka
Vraneš Danijela
Mladenović Zorica
Rusović Siniša
Ratković Nenad
Vukotić Snježana
Torbica Lidija
Milić Veljko
Mišić Tatjana
Ristić Mirjana
Baškot Branislav
Pandrc Milena
author_facet Ristić-Anđelkov Anđelka
Vraneš Danijela
Mladenović Zorica
Rusović Siniša
Ratković Nenad
Vukotić Snježana
Torbica Lidija
Milić Veljko
Mišić Tatjana
Ristić Mirjana
Baškot Branislav
Pandrc Milena
author_sort Ristić-Anđelkov Anđelka
collection DOAJ
description Introduction. Left ventricular noncompaction (LVNC) is a congenital disorder characterised by prominent trabeculations in the left ventricular myocardium. This heart condition very often goes completely undetected, or is mistaken for hypertrophic cardiomyopathy or coronary disease. Case report. A middle-aged female with a positive family history of coronary disease was admitted with chest pain, electrocardiography (ECG) changes in the area of the inferolateral wall and elevation in cardiac specific enzymes. Initially, she was suspected of having acute coronary syndrome. However, in the left ventricular apex, especially alongside the lateral and inferior walls, cardiac ultrasound visualised hypertrabeculation with multiple trabeculae projecting inside the left ventricular cavity. A short-axis view of the heart above the papillary muscles revealed the presence of two layers of the myocardium: a compacted homogeneous layer adjacent to the epicardium and a spongy layer with trabeculae and sinusoids under the endocardium. The thickness ratio between the two layers was 2.2:1. The same abnormalities were corroborated by multislice computed tomography (MSCT) of the heart. Conclusion. Left ventricular noncompaction is a rare, usually hereditary cardiomyopathy, which should be considered as a possibility in patients with myocardial hypertrophy. It is very often mistaken for coronary disease owing to ECG changes and elevated cardiac specific enzymes associated with myocardial hypertrophy and heart failure.
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issn 0042-8450
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publishDate 2018-01-01
publisher Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
record_format Article
series Vojnosanitetski Pregled
spelling doaj-art-75c90df7404847af901aa0757876efb22025-08-20T01:57:52ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202018-01-0175222823310.2298/VSP160124354R0042-84501600354RLeft ventricular noncompaction in a patient presenting with a left ventricular failureRistić-Anđelkov Anđelka0Vraneš Danijela1Mladenović Zorica2Rusović Siniša3Ratković Nenad4Vukotić Snježana5Torbica Lidija6Milić Veljko7Mišić Tatjana8Ristić Mirjana9Baškot Branislav10Pandrc Milena11University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Emergency and Internal Medicine, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Emergency and Internal Medicine, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Cardiology, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute for Radiology, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Emergency and Internal Medicine, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Emergency and Internal Medicine, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Emergency and Internal Medicine, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Emergency and Internal Medicine, BelgradeMilitary Medical Center „Slavija“, BelgradeInternal Medicine Practice „Nada-a“, BelgradeSpecialistic Nuclear Medicine Practice „Dr Baškot“, BelgradeMilitary Medical Center „Slavija“, BelgradeIntroduction. Left ventricular noncompaction (LVNC) is a congenital disorder characterised by prominent trabeculations in the left ventricular myocardium. This heart condition very often goes completely undetected, or is mistaken for hypertrophic cardiomyopathy or coronary disease. Case report. A middle-aged female with a positive family history of coronary disease was admitted with chest pain, electrocardiography (ECG) changes in the area of the inferolateral wall and elevation in cardiac specific enzymes. Initially, she was suspected of having acute coronary syndrome. However, in the left ventricular apex, especially alongside the lateral and inferior walls, cardiac ultrasound visualised hypertrabeculation with multiple trabeculae projecting inside the left ventricular cavity. A short-axis view of the heart above the papillary muscles revealed the presence of two layers of the myocardium: a compacted homogeneous layer adjacent to the epicardium and a spongy layer with trabeculae and sinusoids under the endocardium. The thickness ratio between the two layers was 2.2:1. The same abnormalities were corroborated by multislice computed tomography (MSCT) of the heart. Conclusion. Left ventricular noncompaction is a rare, usually hereditary cardiomyopathy, which should be considered as a possibility in patients with myocardial hypertrophy. It is very often mistaken for coronary disease owing to ECG changes and elevated cardiac specific enzymes associated with myocardial hypertrophy and heart failure.http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600354R.pdfventricular dysfunction, leftheart failureisolated noncompaction of the ventricular myocardiumcoronary vasospasmechocardiographytomographydiagnosis, differential
spellingShingle Ristić-Anđelkov Anđelka
Vraneš Danijela
Mladenović Zorica
Rusović Siniša
Ratković Nenad
Vukotić Snježana
Torbica Lidija
Milić Veljko
Mišić Tatjana
Ristić Mirjana
Baškot Branislav
Pandrc Milena
Left ventricular noncompaction in a patient presenting with a left ventricular failure
Vojnosanitetski Pregled
ventricular dysfunction, left
heart failure
isolated noncompaction of the ventricular myocardium
coronary vasospasm
echocardiography
tomography
diagnosis, differential
title Left ventricular noncompaction in a patient presenting with a left ventricular failure
title_full Left ventricular noncompaction in a patient presenting with a left ventricular failure
title_fullStr Left ventricular noncompaction in a patient presenting with a left ventricular failure
title_full_unstemmed Left ventricular noncompaction in a patient presenting with a left ventricular failure
title_short Left ventricular noncompaction in a patient presenting with a left ventricular failure
title_sort left ventricular noncompaction in a patient presenting with a left ventricular failure
topic ventricular dysfunction, left
heart failure
isolated noncompaction of the ventricular myocardium
coronary vasospasm
echocardiography
tomography
diagnosis, differential
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600354R.pdf
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