Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria.
Urinary tract infection (UTI) is the colonization of the urinary tract by pathogenic microorganisms. There is paucity of data on the development of multidrug resistant uropathogenic strains associated with Diabetes Mellitus (DM). In this cross-sectional study we investigated a total of three hundred...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hammer Head Production Limited
2022-11-01
|
| Series: | Sokoto Journal of Medical Laboratory Science |
| Subjects: | |
| Online Access: | https://sokjmls.com.ng/index.php/SJMLS/article/view/58 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850056472169283584 |
|---|---|
| author | Wathanafa Madu , Musa Joseph Bamaiyi , Monilade Tawa Akinola , Talle Muhammed , Hamidu M. Ibrahim , Idris Nasir 4 3 1,2 1,2 Abdullahi , Muhammad Mustapha , Marycelin Mandu Baba , Bamidele Soji Oderinde |
| author_facet | Wathanafa Madu , Musa Joseph Bamaiyi , Monilade Tawa Akinola , Talle Muhammed , Hamidu M. Ibrahim , Idris Nasir 4 3 1,2 1,2 Abdullahi , Muhammad Mustapha , Marycelin Mandu Baba , Bamidele Soji Oderinde |
| author_sort | Wathanafa Madu , Musa Joseph Bamaiyi , Monilade Tawa Akinola , Talle Muhammed , Hamidu M. Ibrahim , Idris Nasir 4 3 1,2 1,2 Abdullahi , Muhammad Mustapha , Marycelin Mandu Baba , Bamidele Soji Oderinde |
| collection | DOAJ |
| description | Urinary tract infection (UTI) is the colonization of the urinary tract by pathogenic microorganisms. There is paucity of data on the development of multidrug resistant uropathogenic strains associated with Diabetes Mellitus (DM). In this cross-sectional study we investigated a total of three hundred and thirty (330) known diabetes mellitus (DM) patients, comprising of 06 (1.8%) Type I DM, 296 (89.7%) Type II DM and 28 (8.5%) Gestational Diabetes patients aged 21 to 80 years. The subjects consisted of 150 males (45.5%) and 180 (54.5%) females. Urine culture was carried out on CLED, MacConkey and blood agar and Kirby Bauer disc diffusion for antimicrobial susceptibility testing was carried out to determine the susceptibility of the isolated organisms to commonly used antimicrobials in the study area. The study revealed that one hundred and twenty-two (37%) yielded significant bacterial growth. The percentage distribution of the organisms isolated are as follows; Staphylococci (10.6%), Klebsiella spp. (13.2%), Coliforms spp. (13.9%), Staphylococcus aureus (24.6%) and Escherichia coli has the highest occurrence of (37.7%). Gram negative bacteria isolated were highly susceptible to Ciprofloxacin (10 μg), tarivid (10 μg) and streptomycin (30 μg); and moderately- to poorly sensitive to the other antibiotics used in the study. In conclusion female diabetics were at a higher risk for UTIs that than males (p=0.000) and low educational level/social class was also a risk factor (p=0.04) when compared to subjects of higher educational level/ social class. |
| format | Article |
| id | doaj-art-75bdb211a7cc47c78d158a6697977a18 |
| institution | DOAJ |
| issn | 2536-7153 |
| language | English |
| publishDate | 2022-11-01 |
| publisher | Hammer Head Production Limited |
| record_format | Article |
| series | Sokoto Journal of Medical Laboratory Science |
| spelling | doaj-art-75bdb211a7cc47c78d158a6697977a182025-08-20T02:51:42ZengHammer Head Production LimitedSokoto Journal of Medical Laboratory Science2536-71532022-11-017358Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria.Wathanafa Madu , Musa Joseph Bamaiyi , Monilade Tawa Akinola , Talle Muhammed , Hamidu M. Ibrahim , Idris Nasir 4 3 1,2 1,2 Abdullahi , Muhammad Mustapha , Marycelin Mandu Baba , Bamidele Soji OderindeUrinary tract infection (UTI) is the colonization of the urinary tract by pathogenic microorganisms. There is paucity of data on the development of multidrug resistant uropathogenic strains associated with Diabetes Mellitus (DM). In this cross-sectional study we investigated a total of three hundred and thirty (330) known diabetes mellitus (DM) patients, comprising of 06 (1.8%) Type I DM, 296 (89.7%) Type II DM and 28 (8.5%) Gestational Diabetes patients aged 21 to 80 years. The subjects consisted of 150 males (45.5%) and 180 (54.5%) females. Urine culture was carried out on CLED, MacConkey and blood agar and Kirby Bauer disc diffusion for antimicrobial susceptibility testing was carried out to determine the susceptibility of the isolated organisms to commonly used antimicrobials in the study area. The study revealed that one hundred and twenty-two (37%) yielded significant bacterial growth. The percentage distribution of the organisms isolated are as follows; Staphylococci (10.6%), Klebsiella spp. (13.2%), Coliforms spp. (13.9%), Staphylococcus aureus (24.6%) and Escherichia coli has the highest occurrence of (37.7%). Gram negative bacteria isolated were highly susceptible to Ciprofloxacin (10 μg), tarivid (10 μg) and streptomycin (30 μg); and moderately- to poorly sensitive to the other antibiotics used in the study. In conclusion female diabetics were at a higher risk for UTIs that than males (p=0.000) and low educational level/social class was also a risk factor (p=0.04) when compared to subjects of higher educational level/ social class.https://sokjmls.com.ng/index.php/SJMLS/article/view/58antimicrobial susceptibility; uropathogenic organisms; diabetic patients. |
| spellingShingle | Wathanafa Madu , Musa Joseph Bamaiyi , Monilade Tawa Akinola , Talle Muhammed , Hamidu M. Ibrahim , Idris Nasir 4 3 1,2 1,2 Abdullahi , Muhammad Mustapha , Marycelin Mandu Baba , Bamidele Soji Oderinde Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria. Sokoto Journal of Medical Laboratory Science antimicrobial susceptibility; uropathogenic organisms; diabetic patients. |
| title | Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria. |
| title_full | Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria. |
| title_fullStr | Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria. |
| title_full_unstemmed | Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria. |
| title_short | Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria. |
| title_sort | prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending state specialist hospital maiduguri nigeria |
| topic | antimicrobial susceptibility; uropathogenic organisms; diabetic patients. |
| url | https://sokjmls.com.ng/index.php/SJMLS/article/view/58 |
| work_keys_str_mv | AT wathanafamadumusajosephbamaiyimoniladetawaakinolatallemuhammedhamidumibrahimidrisnasir431212abdullahimuhammadmustaphamarycelinmandubababamidelesojioderinde prevalenceandantimicrobialsusceptibilitypatternofuropathogenicorganismsamongdiabeticpatientsattendingstatespecialisthospitalmaidugurinigeria |