The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis

Objective Leptin is an appetite-suppressing hormone released by adipose tissue that plays an important role in severe obstructive sleep apnea syndrome (OSAS). However, it is unclear whether leptin levels are a useful biomarker for this syndrome. The present study aimed to assess the effec...

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Main Authors: Takashi Oki, Yutaka Kozu, Mamiko Hoshi, Yasunori Itoda, Naho Furusho, Ryosuke Ozoe, Yusuke Jinno, Akifumi Hirata, Yusuke Kurosawa, Shiho Yamada, Asami Fukuda, Mari Hikichi, Sotaro Shikano, Kenichi Sugaya, Hisato Hiranuma, Shuichiro Maruoka, Yasuhiro Gon
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2024-06-01
Series:Sleep Science
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1777779
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author Takashi Oki
Yutaka Kozu
Mamiko Hoshi
Yasunori Itoda
Naho Furusho
Ryosuke Ozoe
Yusuke Jinno
Akifumi Hirata
Yusuke Kurosawa
Shiho Yamada
Asami Fukuda
Mari Hikichi
Sotaro Shikano
Kenichi Sugaya
Hisato Hiranuma
Shuichiro Maruoka
Yasuhiro Gon
author_facet Takashi Oki
Yutaka Kozu
Mamiko Hoshi
Yasunori Itoda
Naho Furusho
Ryosuke Ozoe
Yusuke Jinno
Akifumi Hirata
Yusuke Kurosawa
Shiho Yamada
Asami Fukuda
Mari Hikichi
Sotaro Shikano
Kenichi Sugaya
Hisato Hiranuma
Shuichiro Maruoka
Yasuhiro Gon
author_sort Takashi Oki
collection DOAJ
description Objective Leptin is an appetite-suppressing hormone released by adipose tissue that plays an important role in severe obstructive sleep apnea syndrome (OSAS). However, it is unclear whether leptin levels are a useful biomarker for this syndrome. The present study aimed to assess the effect of continuous positive airway pressure (CPAP) treatment on the syndrome according to leptin levels, using a cluster classification based on clinical features of the syndrome.
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issn 1984-0659
1984-0063
language English
publishDate 2024-06-01
publisher Thieme Revinter Publicações Ltda.
record_format Article
series Sleep Science
spelling doaj-art-75af7ff4b2da4559933c04a2e7ea83622025-08-20T02:11:30ZengThieme Revinter Publicações Ltda.Sleep Science1984-06591984-00632024-06-011702e143e15010.1055/s-0043-1777779The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster AnalysisTakashi Oki0Yutaka Kozu1https://orcid.org/0000-0003-4472-3625Mamiko Hoshi2Yasunori Itoda3Naho Furusho4Ryosuke Ozoe5Yusuke Jinno6Akifumi Hirata7Yusuke Kurosawa8Shiho Yamada9Asami Fukuda10Mari Hikichi11Sotaro Shikano12Kenichi Sugaya13Hisato Hiranuma14Shuichiro Maruoka15Yasuhiro Gon16Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, JapanDepartment of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan Objective Leptin is an appetite-suppressing hormone released by adipose tissue that plays an important role in severe obstructive sleep apnea syndrome (OSAS). However, it is unclear whether leptin levels are a useful biomarker for this syndrome. The present study aimed to assess the effect of continuous positive airway pressure (CPAP) treatment on the syndrome according to leptin levels, using a cluster classification based on clinical features of the syndrome.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1777779obstructive sleep apneaphenotypecluster analysisleptincontinuous positive airway pressure
spellingShingle Takashi Oki
Yutaka Kozu
Mamiko Hoshi
Yasunori Itoda
Naho Furusho
Ryosuke Ozoe
Yusuke Jinno
Akifumi Hirata
Yusuke Kurosawa
Shiho Yamada
Asami Fukuda
Mari Hikichi
Sotaro Shikano
Kenichi Sugaya
Hisato Hiranuma
Shuichiro Maruoka
Yasuhiro Gon
The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis
Sleep Science
obstructive sleep apnea
phenotype
cluster analysis
leptin
continuous positive airway pressure
title The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis
title_full The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis
title_fullStr The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis
title_full_unstemmed The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis
title_short The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis
title_sort relationship between leptin levels and continuous positive airway pressure treatment a cluster analysis
topic obstructive sleep apnea
phenotype
cluster analysis
leptin
continuous positive airway pressure
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1777779
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