Prevalence of Hypocalcemia in Infants of Mothers with Gestational Diabetes

Objective: To evaluate the prevalence of newborn hypocalcemia among infants of mothers with gestational diabetes. Study Design & Setting: This cross-sectional study was conducted at PNS Shifa Hospital, Karachi, from November 2023 to March 2024 Methodology: Each mother's fasting blood su...

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Main Authors: Nida Sarwar, Khurram Fayyaz, Imrana Ata, Sehar Aslam, Hajra Begum, Khubaib Ahmad
Format: Article
Language:English
Published: Bahria Univerisy Health Sciences, Campus Karachi 2025-01-01
Series:Journal of Bahria University Medical and Dental College
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Online Access:https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/1631
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author Nida Sarwar
Khurram Fayyaz
Imrana Ata
Sehar Aslam
Hajra Begum
Khubaib Ahmad
author_facet Nida Sarwar
Khurram Fayyaz
Imrana Ata
Sehar Aslam
Hajra Begum
Khubaib Ahmad
author_sort Nida Sarwar
collection DOAJ
description Objective: To evaluate the prevalence of newborn hypocalcemia among infants of mothers with gestational diabetes. Study Design & Setting: This cross-sectional study was conducted at PNS Shifa Hospital, Karachi, from November 2023 to March 2024 Methodology: Each mother's fasting blood sugar level was evaluated by drawing 5 ml of blood. At 24 hours after delivery, sterile blood samples (2 cc) were taken to determine the neonate's calcium level; a serum calcium level below 7 mg/dl was regarded as hypocalcemia. All information was gathered using a research template that was created in-house. Serum calcium was measured using the Arsenazo III method, and serum albumin was assessed using the bromocresol green (BCG) method. Results: The mean ± S.D. of the maternal age of the study participants was 26.83 ± 3.87 years. The mean ± S.D. of the gestational age of the study participants was 37.35 ± 0.86 weeks. The mean ± S.D. of fasting glucose levels of the study participants was 104.5 ± 15.1 mg/dl. A total of 27.5% of infants born to mothers with gestational diabetes had hypocalcemia. Infants' median Apgar scores at 1 and 5 minutes were 6 and 9, respectively. The prevalence of hypocalcemia in newborns was highest among mothers aged 21–30, though this difference was not statistically significant (p = 0.139). Conclusion: The results showed that 27.5% of infants born to mothers with gestational diabetes had hypocalcemia. Maternal age did not have a statistically significant association with hypocalcemia in newborns.
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spelling doaj-art-75a7e2c6cb704259bc92b0a5d43ae7222025-08-20T03:13:18ZengBahria Univerisy Health Sciences, Campus KarachiJournal of Bahria University Medical and Dental College2220-75622617-94822025-01-01150110.51985/JBUMDC20244191631Prevalence of Hypocalcemia in Infants of Mothers with Gestational DiabetesNida SarwarKhurram FayyazImrana AtaSehar AslamHajra BegumKhubaib Ahmad Objective: To evaluate the prevalence of newborn hypocalcemia among infants of mothers with gestational diabetes. Study Design & Setting: This cross-sectional study was conducted at PNS Shifa Hospital, Karachi, from November 2023 to March 2024 Methodology: Each mother's fasting blood sugar level was evaluated by drawing 5 ml of blood. At 24 hours after delivery, sterile blood samples (2 cc) were taken to determine the neonate's calcium level; a serum calcium level below 7 mg/dl was regarded as hypocalcemia. All information was gathered using a research template that was created in-house. Serum calcium was measured using the Arsenazo III method, and serum albumin was assessed using the bromocresol green (BCG) method. Results: The mean ± S.D. of the maternal age of the study participants was 26.83 ± 3.87 years. The mean ± S.D. of the gestational age of the study participants was 37.35 ± 0.86 weeks. The mean ± S.D. of fasting glucose levels of the study participants was 104.5 ± 15.1 mg/dl. A total of 27.5% of infants born to mothers with gestational diabetes had hypocalcemia. Infants' median Apgar scores at 1 and 5 minutes were 6 and 9, respectively. The prevalence of hypocalcemia in newborns was highest among mothers aged 21–30, though this difference was not statistically significant (p = 0.139). Conclusion: The results showed that 27.5% of infants born to mothers with gestational diabetes had hypocalcemia. Maternal age did not have a statistically significant association with hypocalcemia in newborns. https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/1631Hypocalcemia, Infants, Gestational Diabetes, Maternal Hyperglycemia
spellingShingle Nida Sarwar
Khurram Fayyaz
Imrana Ata
Sehar Aslam
Hajra Begum
Khubaib Ahmad
Prevalence of Hypocalcemia in Infants of Mothers with Gestational Diabetes
Journal of Bahria University Medical and Dental College
Hypocalcemia, Infants, Gestational Diabetes, Maternal Hyperglycemia
title Prevalence of Hypocalcemia in Infants of Mothers with Gestational Diabetes
title_full Prevalence of Hypocalcemia in Infants of Mothers with Gestational Diabetes
title_fullStr Prevalence of Hypocalcemia in Infants of Mothers with Gestational Diabetes
title_full_unstemmed Prevalence of Hypocalcemia in Infants of Mothers with Gestational Diabetes
title_short Prevalence of Hypocalcemia in Infants of Mothers with Gestational Diabetes
title_sort prevalence of hypocalcemia in infants of mothers with gestational diabetes
topic Hypocalcemia, Infants, Gestational Diabetes, Maternal Hyperglycemia
url https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/1631
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