Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase
Acute moderate exercise has been shown to induce prolonged changes in functional connectivity (FC) within affect and reward networks. The influence of different exercise intensities on FC has not yet been explored. Twenty-five male athletes underwent 30 min of “low”- (35%<lactate threshold (LT))...
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| Format: | Article |
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Wiley
2020-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2020/7905387 |
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| author | Angelika Schmitt Neeraj Upadhyay Jason Anthony Martin Sandra Rojas Vega Heiko Klaus Strüder Henning Boecker |
| author_facet | Angelika Schmitt Neeraj Upadhyay Jason Anthony Martin Sandra Rojas Vega Heiko Klaus Strüder Henning Boecker |
| author_sort | Angelika Schmitt |
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| description | Acute moderate exercise has been shown to induce prolonged changes in functional connectivity (FC) within affect and reward networks. The influence of different exercise intensities on FC has not yet been explored. Twenty-five male athletes underwent 30 min of “low”- (35%<lactate threshold (LT)) and “high”- (20%>LT) intensity exercise bouts on a treadmill. Resting-state fMRI was acquired at 3 Tesla before and after exercise, together with the Positive and Negative Affect Scale (PANAS). Data of 22 subjects (3 dropouts) were analyzed using the FSL feat pipeline and a seed-to-network-based analysis with the bilateral amygdala as the seed region for determining associated FC changes in the “emotional brain.” Data were analyzed using a repeated measures ANOVA. Comparisons between pre- and post-exercise were analyzed using a one-sample t-test, and a paired t-test was used for the comparison between “low” and “high” exercise conditions (nonparametric randomization approach, results reported at p<0.05). Both exercise interventions induced significant increases in the PANAS positive affect scale. There was a significant interaction effect of amygdalar FC to the right anterior insula, and this amygdalar-insular FC correlated significantly with the PANAS positive affect scale (r=0.47, p=0.048) in the “high”-intensity exercise condition. Our findings suggest that mood changes after exercise are associated with prolonged alterations in amygdalar-insular FC and occur in an exercise intensity-dependent manner. |
| format | Article |
| id | doaj-art-75a43586d0f2437ab9c14171bcc538cc |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
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| series | Neural Plasticity |
| spelling | doaj-art-75a43586d0f2437ab9c14171bcc538cc2025-08-20T03:35:22ZengWileyNeural Plasticity2090-59041687-54432020-01-01202010.1155/2020/79053877905387Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity IncreaseAngelika Schmitt0Neeraj Upadhyay1Jason Anthony Martin2Sandra Rojas Vega3Heiko Klaus Strüder4Henning Boecker5Functional Neuroimaging Group, Clinic for Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, Building 7, 53127 Bonn, GermanyGerman Center for Neurodegenerative Diseases, Venusberg-Campus 1, Building 99, 53127 Bonn, GermanyFunctional Neuroimaging Group, Clinic for Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, Building 7, 53127 Bonn, GermanyInstitute of Movement and Neurosciences, German Sport University, Am Sportpark Müngersdorf 6, 50933 Cologne, GermanyInstitute of Movement and Neurosciences, German Sport University, Am Sportpark Müngersdorf 6, 50933 Cologne, GermanyFunctional Neuroimaging Group, Clinic for Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, Building 7, 53127 Bonn, GermanyAcute moderate exercise has been shown to induce prolonged changes in functional connectivity (FC) within affect and reward networks. The influence of different exercise intensities on FC has not yet been explored. Twenty-five male athletes underwent 30 min of “low”- (35%<lactate threshold (LT)) and “high”- (20%>LT) intensity exercise bouts on a treadmill. Resting-state fMRI was acquired at 3 Tesla before and after exercise, together with the Positive and Negative Affect Scale (PANAS). Data of 22 subjects (3 dropouts) were analyzed using the FSL feat pipeline and a seed-to-network-based analysis with the bilateral amygdala as the seed region for determining associated FC changes in the “emotional brain.” Data were analyzed using a repeated measures ANOVA. Comparisons between pre- and post-exercise were analyzed using a one-sample t-test, and a paired t-test was used for the comparison between “low” and “high” exercise conditions (nonparametric randomization approach, results reported at p<0.05). Both exercise interventions induced significant increases in the PANAS positive affect scale. There was a significant interaction effect of amygdalar FC to the right anterior insula, and this amygdalar-insular FC correlated significantly with the PANAS positive affect scale (r=0.47, p=0.048) in the “high”-intensity exercise condition. Our findings suggest that mood changes after exercise are associated with prolonged alterations in amygdalar-insular FC and occur in an exercise intensity-dependent manner.http://dx.doi.org/10.1155/2020/7905387 |
| spellingShingle | Angelika Schmitt Neeraj Upadhyay Jason Anthony Martin Sandra Rojas Vega Heiko Klaus Strüder Henning Boecker Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase Neural Plasticity |
| title | Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase |
| title_full | Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase |
| title_fullStr | Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase |
| title_full_unstemmed | Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase |
| title_short | Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase |
| title_sort | affective modulation after high intensity exercise is associated with prolonged amygdalar insular functional connectivity increase |
| url | http://dx.doi.org/10.1155/2020/7905387 |
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