Comorbid infections in patients with systemic lupus erythematosus: State-of-the-art

In modern rheumatology, comorbid infections (CIs) have a significant impact on morbidity and mortality of patients with systemic lupus erythematosus (SLE). The increased susceptibility of SLE patients to infections is associated with various immune disorders. A number of risk factors for CIs in SLE,...

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Main Authors: B. S. Belov, S. K. Solovyev, N. G. Klyukvina, G. M. Tarasova, M. V. Polyanskaya M.V.
Format: Article
Language:Russian
Published: IMA PRESS LLC 2016-10-01
Series:Научно-практическая ревматология
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Online Access:https://rsp.mediar-press.net/rsp/article/view/2278
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author B. S. Belov
S. K. Solovyev
N. G. Klyukvina
G. M. Tarasova
M. V. Polyanskaya M.V.
author_facet B. S. Belov
S. K. Solovyev
N. G. Klyukvina
G. M. Tarasova
M. V. Polyanskaya M.V.
author_sort B. S. Belov
collection DOAJ
description In modern rheumatology, comorbid infections (CIs) have a significant impact on morbidity and mortality of patients with systemic lupus erythematosus (SLE). The increased susceptibility of SLE patients to infections is associated with various immune disorders. A number of risk factors for CIs in SLE, which are related to the disease and its treatment, have been identified. However, despite the fact that there are a sufficient number of these factors, the contribution of each of them varies considerably with the cohort of examined SLE patients. The paper considers the epidemiological, clinical, and laboratory characteristics of some bacterial and viral CIs in patients with SLE in current clinical practice. It underlines the importance of primarily influenza and pneumococcal vaccination in patients with SLE since among them the risk of deaths from lower respiratory tract infections is quite high. The ways of further investigations in the framework of the problem under consideration are outlined.
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language Russian
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record_format Article
series Научно-практическая ревматология
spelling doaj-art-75a1b2596d784b0e88b7f41dbea1d31d2025-08-20T02:55:19ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922016-10-0154446947710.14412/1995-4484-2016-469-4772144Comorbid infections in patients with systemic lupus erythematosus: State-of-the-artB. S. Belov0S. K. Solovyev1N. G. Klyukvina2G. M. Tarasova3M. V. Polyanskaya M.V.4V.A. Nasonova Research Institute of Rheumatology, MoscowV.A. Nasonova Research Institute of Rheumatology, MoscowI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, MoscowV.A. Nasonova Research Institute of Rheumatology, MoscowV.A. Nasonova Research Institute of Rheumatology, MoscowIn modern rheumatology, comorbid infections (CIs) have a significant impact on morbidity and mortality of patients with systemic lupus erythematosus (SLE). The increased susceptibility of SLE patients to infections is associated with various immune disorders. A number of risk factors for CIs in SLE, which are related to the disease and its treatment, have been identified. However, despite the fact that there are a sufficient number of these factors, the contribution of each of them varies considerably with the cohort of examined SLE patients. The paper considers the epidemiological, clinical, and laboratory characteristics of some bacterial and viral CIs in patients with SLE in current clinical practice. It underlines the importance of primarily influenza and pneumococcal vaccination in patients with SLE since among them the risk of deaths from lower respiratory tract infections is quite high. The ways of further investigations in the framework of the problem under consideration are outlined.https://rsp.mediar-press.net/rsp/article/view/2278systemic lupus erythematosusbacterial infectionsviral infectionsvaccination
spellingShingle B. S. Belov
S. K. Solovyev
N. G. Klyukvina
G. M. Tarasova
M. V. Polyanskaya M.V.
Comorbid infections in patients with systemic lupus erythematosus: State-of-the-art
Научно-практическая ревматология
systemic lupus erythematosus
bacterial infections
viral infections
vaccination
title Comorbid infections in patients with systemic lupus erythematosus: State-of-the-art
title_full Comorbid infections in patients with systemic lupus erythematosus: State-of-the-art
title_fullStr Comorbid infections in patients with systemic lupus erythematosus: State-of-the-art
title_full_unstemmed Comorbid infections in patients with systemic lupus erythematosus: State-of-the-art
title_short Comorbid infections in patients with systemic lupus erythematosus: State-of-the-art
title_sort comorbid infections in patients with systemic lupus erythematosus state of the art
topic systemic lupus erythematosus
bacterial infections
viral infections
vaccination
url https://rsp.mediar-press.net/rsp/article/view/2278
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