Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over Time
Postherpetic itch (PHI), or herpes zoster itch, is an intractable and poorly understood disease. We targeted 94 herpes zoster patients to investigate their pain and itch intensities at three separate stages of the condition (acute, subacute, and chronic). We used painDETECT questionnaire (PDQ) score...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2018/9305126 |
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| author | Rie Ishikawa Masako Iseki Rie Koga Eiichi Inada |
| author_facet | Rie Ishikawa Masako Iseki Rie Koga Eiichi Inada |
| author_sort | Rie Ishikawa |
| collection | DOAJ |
| description | Postherpetic itch (PHI), or herpes zoster itch, is an intractable and poorly understood disease. We targeted 94 herpes zoster patients to investigate their pain and itch intensities at three separate stages of the condition (acute, subacute, and chronic). We used painDETECT questionnaire (PDQ) scores to investigate the correlation between PHI and neuropathic pain. Seventy-six patients were able to complete follow-up surveys. The prevalence of PHI was 47/76 (62%), 28/76 (37%), and 34/76 (45%) at the acute, subacute, and chronic stages, respectively. PHI manifestation times and patterns varied. We investigated the relationship of PHI with neuropathic pain using the visual analog scale (VAS), which is a measure of pain intensity, and the PDQ, which is a questionnaire used to evaluate the elements of neuropathic pain. The VAS and PDQ scores did not differ significantly between PHI-positive and PHI-negative patients. A large neuropathic component was not found for herpes zoster itch, suggesting that neuropathic pain treatments may not able to adequately control the itch. Accordingly, we suggest that a more PHI-focused therapy is required to address this condition. |
| format | Article |
| id | doaj-art-759f978a92e648fb96623abdc870217b |
| institution | Kabale University |
| issn | 1203-6765 1918-1523 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-759f978a92e648fb96623abdc870217b2025-02-03T01:22:54ZengWileyPain Research and Management1203-67651918-15232018-01-01201810.1155/2018/93051269305126Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over TimeRie Ishikawa0Masako Iseki1Rie Koga2Eiichi Inada3Department of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, 1-3 Hongo 3-chome, Bunkyo-ku 113-8431, JapanDepartment of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, 1-3 Hongo 3-chome, Bunkyo-ku 113-8431, JapanDepartment of Pain Medicine, Sata Hospital, 4-28 Watanabedori 2-chome, Chuo-ku 810-0004, JapanDepartment of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, 1-3 Hongo 3-chome, Bunkyo-ku 113-8431, JapanPostherpetic itch (PHI), or herpes zoster itch, is an intractable and poorly understood disease. We targeted 94 herpes zoster patients to investigate their pain and itch intensities at three separate stages of the condition (acute, subacute, and chronic). We used painDETECT questionnaire (PDQ) scores to investigate the correlation between PHI and neuropathic pain. Seventy-six patients were able to complete follow-up surveys. The prevalence of PHI was 47/76 (62%), 28/76 (37%), and 34/76 (45%) at the acute, subacute, and chronic stages, respectively. PHI manifestation times and patterns varied. We investigated the relationship of PHI with neuropathic pain using the visual analog scale (VAS), which is a measure of pain intensity, and the PDQ, which is a questionnaire used to evaluate the elements of neuropathic pain. The VAS and PDQ scores did not differ significantly between PHI-positive and PHI-negative patients. A large neuropathic component was not found for herpes zoster itch, suggesting that neuropathic pain treatments may not able to adequately control the itch. Accordingly, we suggest that a more PHI-focused therapy is required to address this condition.http://dx.doi.org/10.1155/2018/9305126 |
| spellingShingle | Rie Ishikawa Masako Iseki Rie Koga Eiichi Inada Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over Time Pain Research and Management |
| title | Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over Time |
| title_full | Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over Time |
| title_fullStr | Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over Time |
| title_full_unstemmed | Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over Time |
| title_short | Investigation of the Correlation between Postherpetic Itch and Neuropathic Pain over Time |
| title_sort | investigation of the correlation between postherpetic itch and neuropathic pain over time |
| url | http://dx.doi.org/10.1155/2018/9305126 |
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