Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD
Is steatosis related to the spontaneous carbohydrate intake in patients with NAFLD? We performed dietary records for 24 patients with NAFLD, 3 months after their liver biopsy was performed and before the deliverance of a dietary advice. The food quotient, indicator of the proportion of calories from...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/428542 |
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| author | Concepcion Gonzalez Victor de Ledinghen Julien Vergniol Juliette Foucher Brigitte Le Bail Sabrina Carlier Elisa Maury Henri Gin Vincent Rigalleau |
| author_facet | Concepcion Gonzalez Victor de Ledinghen Julien Vergniol Juliette Foucher Brigitte Le Bail Sabrina Carlier Elisa Maury Henri Gin Vincent Rigalleau |
| author_sort | Concepcion Gonzalez |
| collection | DOAJ |
| description | Is steatosis related to the spontaneous carbohydrate intake in patients with NAFLD? We performed dietary records for 24 patients with NAFLD, 3 months after their liver biopsy was performed and before the deliverance of a dietary advice. The food quotient, indicator of the proportion of calories from carbohydrates, was calculated as (1.00×% calories from carbohydrates/100) + (0.70×% calories from lipids/100) + (0.81×% calories from proteins/100). The associations between diet variables and steatosis% on the hepatic biopsies were tested by regression analysis, and diet variables were compared according to the presence of fibrosis. The subjects displayed a large range of steatosis, 50.5% ± 25.5 [10–90], correlated with their energy intake (1993 ± 597 kcal/d, , ) and food quotient (0.85 ± 0.02, , ), which remained significant with both variables by a multivariate regression analysis (, ). For the 17/24 patients with a hepatic fibrosis, the energy intake was lower (fibrosis: 1863 ± 503 versus others: 2382 ± 733 kcal/d, ), and their food quotients did not differ from patients without fibrosis. Hepatic steatosis was related to the energy and carbohydrate intakes in our patients; the role of dietary carbohydrates was detectable in the range of usual carbohydrate intake: 32% to 58% calories. |
| format | Article |
| id | doaj-art-759a4d60869f43dd9a8fac945b227057 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-759a4d60869f43dd9a8fac945b2270572025-02-03T06:08:24ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/428542428542Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLDConcepcion Gonzalez0Victor de Ledinghen1Julien Vergniol2Juliette Foucher3Brigitte Le Bail4Sabrina Carlier5Elisa Maury6Henri Gin7Vincent Rigalleau8Pôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, FrancePôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, FrancePôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, FrancePôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, FranceService de Pathologie, CHU de Bordeaux, FrancePôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, FrancePôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, FrancePôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, FrancePôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, FranceIs steatosis related to the spontaneous carbohydrate intake in patients with NAFLD? We performed dietary records for 24 patients with NAFLD, 3 months after their liver biopsy was performed and before the deliverance of a dietary advice. The food quotient, indicator of the proportion of calories from carbohydrates, was calculated as (1.00×% calories from carbohydrates/100) + (0.70×% calories from lipids/100) + (0.81×% calories from proteins/100). The associations between diet variables and steatosis% on the hepatic biopsies were tested by regression analysis, and diet variables were compared according to the presence of fibrosis. The subjects displayed a large range of steatosis, 50.5% ± 25.5 [10–90], correlated with their energy intake (1993 ± 597 kcal/d, , ) and food quotient (0.85 ± 0.02, , ), which remained significant with both variables by a multivariate regression analysis (, ). For the 17/24 patients with a hepatic fibrosis, the energy intake was lower (fibrosis: 1863 ± 503 versus others: 2382 ± 733 kcal/d, ), and their food quotients did not differ from patients without fibrosis. Hepatic steatosis was related to the energy and carbohydrate intakes in our patients; the role of dietary carbohydrates was detectable in the range of usual carbohydrate intake: 32% to 58% calories.http://dx.doi.org/10.1155/2013/428542 |
| spellingShingle | Concepcion Gonzalez Victor de Ledinghen Julien Vergniol Juliette Foucher Brigitte Le Bail Sabrina Carlier Elisa Maury Henri Gin Vincent Rigalleau Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD International Journal of Endocrinology |
| title | Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD |
| title_full | Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD |
| title_fullStr | Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD |
| title_full_unstemmed | Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD |
| title_short | Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD |
| title_sort | hepatic steatosis carbohydrate intake and food quotient in patients with nafld |
| url | http://dx.doi.org/10.1155/2013/428542 |
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