The Novel Use of Daratumumab in the Treatment of Refractory Autoimmune Pulmonary Alveolar Proteinosis
ABSTRACT Autoimmune pulmonary alveolar proteinosis (aPAP) is caused by circulating anti‐granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) auto‐antibodies that impair alveolar macrophage and neutrophil function. Macrophage dysfunction leads to accumulation of protein‐ and lipid‐rich surfactan...
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| Main Authors: | April Strong, Ying Sun, David Pilcher, Zane Kaplan, Rob G. Stirling |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-06-01
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| Series: | Respirology Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rcr2.70246 |
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