Optical Quality and Related Factors in Ocular Hypertension: Preliminary Study

Background. To evaluate the optical quality and related factors in patients with ocular hypertension (OHT). Methods. This was a prospective case-control study. A total of 12 eyes with OHT and 20 control eyes underwent testing with Optical Quality Analysis System II (OQAS II) to evaluate the modulati...

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Main Authors: Yu-jing Wang, Yan-ning Yang, Lin-ying Huang, Bo Wang, Yu-can Han, Jiang-bo Yan
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2016/3071036
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author Yu-jing Wang
Yan-ning Yang
Lin-ying Huang
Bo Wang
Yu-can Han
Jiang-bo Yan
author_facet Yu-jing Wang
Yan-ning Yang
Lin-ying Huang
Bo Wang
Yu-can Han
Jiang-bo Yan
author_sort Yu-jing Wang
collection DOAJ
description Background. To evaluate the optical quality and related factors in patients with ocular hypertension (OHT). Methods. This was a prospective case-control study. A total of 12 eyes with OHT and 20 control eyes underwent testing with Optical Quality Analysis System II (OQAS II) to evaluate the modulation transfer function cut off frequency (MTF cutoff), the Strehl 2D ratio (SR), objective scatter index (OSI), tear-film mean OSI (TFOSI), and the OQAS values (OV100%,OV20%, and OV9%). Results. The optical quality of patients with OHT declined, with lower MTF cutoff (OHT 36.86 ± 7.11 cpd , controls 48.50 ± 4.04 cpd, t=-4.60, P<0.05), lower SR (OHT 0.22 ± 0.04, controls 0.27 ± 0.05, t=-2.72, P<0.05), lower OV100% (OHT 1.26 ± 0.25, controls 1.61 ± 0.14, t=-4.03, P<0.05), lower OV20% (OHT 1.27 ± 0.27, controls 1.72 ± 0.20, t=-4.00, P<0.05), and lower OV9% (OHT 1.30 ± 0.25, controls 1.69 ± 0.32, t=-2.28, P<0.05). There were not any statistically significant differences in OSI and TFOSI. The MTF cutoff in patients with OHT was correlated significantly with age (r=-0.59, P<0.05). Conclusions. Optical quality of patients with OHT is reduced, with lower MTF cutoff, SR, OV100%, OV20%, and OV9%. MTF cutoff is negatively related to age.
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spelling doaj-art-758f265dfb3248caa7f0b3d25e0eff572025-08-20T02:06:57ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/30710363071036Optical Quality and Related Factors in Ocular Hypertension: Preliminary StudyYu-jing Wang0Yan-ning Yang1Lin-ying Huang2Bo Wang3Yu-can Han4Jiang-bo Yan5Department of ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, ChinaDepartment of ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, ChinaDepartment of ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, ChinaDepartment of ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, ChinaDepartment of ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, ChinaDepartment of ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, ChinaBackground. To evaluate the optical quality and related factors in patients with ocular hypertension (OHT). Methods. This was a prospective case-control study. A total of 12 eyes with OHT and 20 control eyes underwent testing with Optical Quality Analysis System II (OQAS II) to evaluate the modulation transfer function cut off frequency (MTF cutoff), the Strehl 2D ratio (SR), objective scatter index (OSI), tear-film mean OSI (TFOSI), and the OQAS values (OV100%,OV20%, and OV9%). Results. The optical quality of patients with OHT declined, with lower MTF cutoff (OHT 36.86 ± 7.11 cpd , controls 48.50 ± 4.04 cpd, t=-4.60, P<0.05), lower SR (OHT 0.22 ± 0.04, controls 0.27 ± 0.05, t=-2.72, P<0.05), lower OV100% (OHT 1.26 ± 0.25, controls 1.61 ± 0.14, t=-4.03, P<0.05), lower OV20% (OHT 1.27 ± 0.27, controls 1.72 ± 0.20, t=-4.00, P<0.05), and lower OV9% (OHT 1.30 ± 0.25, controls 1.69 ± 0.32, t=-2.28, P<0.05). There were not any statistically significant differences in OSI and TFOSI. The MTF cutoff in patients with OHT was correlated significantly with age (r=-0.59, P<0.05). Conclusions. Optical quality of patients with OHT is reduced, with lower MTF cutoff, SR, OV100%, OV20%, and OV9%. MTF cutoff is negatively related to age.http://dx.doi.org/10.1155/2016/3071036
spellingShingle Yu-jing Wang
Yan-ning Yang
Lin-ying Huang
Bo Wang
Yu-can Han
Jiang-bo Yan
Optical Quality and Related Factors in Ocular Hypertension: Preliminary Study
Journal of Ophthalmology
title Optical Quality and Related Factors in Ocular Hypertension: Preliminary Study
title_full Optical Quality and Related Factors in Ocular Hypertension: Preliminary Study
title_fullStr Optical Quality and Related Factors in Ocular Hypertension: Preliminary Study
title_full_unstemmed Optical Quality and Related Factors in Ocular Hypertension: Preliminary Study
title_short Optical Quality and Related Factors in Ocular Hypertension: Preliminary Study
title_sort optical quality and related factors in ocular hypertension preliminary study
url http://dx.doi.org/10.1155/2016/3071036
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