Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials.

Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials.

This study identifies the secondary metabolites from Alternaria alternate and evaluates their ACE-2: Spike RBD (SARS-CoV-2) inhibitory activity confirmed via immunoblotting in human lung microvascular endothelial cells. In addition, their in vitro anti-inflammatory potential was assessed using a cel...

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Main Authors: Fatma A Moharram, Reham R Ibrahim, Shahenda Mahgoub, Mohamed S Abdel-Aziz, Ahmed M Said, Hui-Chi Huang, Lo-Yun Chen, Kuei-Hung Lai, Nashwa Hashad, Mohamed S Mady
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0313616
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