Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6
Abstract Natural killer (NK) cell development and functionality rely on precise regulation by specific transcription factors (TFs). Our study demonstrates that the nuclear orphan receptor NR2F6 represses the expression of the activating receptor NKp46, an established key player in NK cell-mediated c...
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Main Authors: | Johannes Woelk, Florian Hornsteiner, Stephanie Aschauer-Wallner, Patrizia Stoitzner, Gottfried Baier, Natascha Hermann-Kleiter |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2025-02-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-025-07407-4 |
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