Biological targeted therapy for type 2 inflammation bronchial asthma
Bronchial asthma is a chronic inflammatory disease of the airway involving multiple inflammatory cells and cytokines. Severe asthma is characterized by recurrent attacks and persistent symptoms such as coughing， chest tightness， shortness of breath， and wheezing， etc.， which are difficult to be alle...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of New Medicine
2024-11-01
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| Series: | Xin yixue |
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| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1735545799799-688098850.pdf |
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| author | ZHANG Mingqiang, MU Xiangdong |
| author_facet | ZHANG Mingqiang, MU Xiangdong |
| author_sort | ZHANG Mingqiang, MU Xiangdong |
| collection | DOAJ |
| description | Bronchial asthma is a chronic inflammatory disease of the airway involving multiple inflammatory cells and cytokines. Severe asthma is characterized by recurrent attacks and persistent symptoms such as coughing， chest tightness， shortness of breath， and wheezing， etc.， which are difficult to be alleviated and have a significant impact on the quality of life of patients. At present， the standard therapy of combining high-dose inhaled corticosteroids and long-acting bronchodilators is recommended， but asthma symptoms of certain patients cannot be fully controlled， which is primarily related to persistent type 2 inflammation. For severe asthma patients with persistent type 2 inflammation， biological targeted drugs can be chosen. Biological targeted therapy can significantly mitigate symptoms， reduce the frequency of acute exacerbations and oral use of corticosteroids， bringing new hope to asthma patients with severe type 2 inflammation. This article reviews the research progress in biological targeted therapy for type 2 inflammation in patients with bronchial asthma. |
| format | Article |
| id | doaj-art-758754687ac34b0daeec0dadcd45ba60 |
| institution | DOAJ |
| issn | 0253-9802 |
| language | zho |
| publishDate | 2024-11-01 |
| publisher | Editorial Office of Journal of New Medicine |
| record_format | Article |
| series | Xin yixue |
| spelling | doaj-art-758754687ac34b0daeec0dadcd45ba602025-08-20T02:39:56ZzhoEditorial Office of Journal of New MedicineXin yixue0253-98022024-11-01551194494910.3969/j.issn.0253-9802.2024.11.012Biological targeted therapy for type 2 inflammation bronchial asthmaZHANG Mingqiang, MU Xiangdong0Department of Pulmonary and Critical Care Medicine，Beijing Tsinghua Changgung Hospital， School of Clinical Medicine, Tsinghua University， Beijing 102218， ChinaBronchial asthma is a chronic inflammatory disease of the airway involving multiple inflammatory cells and cytokines. Severe asthma is characterized by recurrent attacks and persistent symptoms such as coughing， chest tightness， shortness of breath， and wheezing， etc.， which are difficult to be alleviated and have a significant impact on the quality of life of patients. At present， the standard therapy of combining high-dose inhaled corticosteroids and long-acting bronchodilators is recommended， but asthma symptoms of certain patients cannot be fully controlled， which is primarily related to persistent type 2 inflammation. For severe asthma patients with persistent type 2 inflammation， biological targeted drugs can be chosen. Biological targeted therapy can significantly mitigate symptoms， reduce the frequency of acute exacerbations and oral use of corticosteroids， bringing new hope to asthma patients with severe type 2 inflammation. This article reviews the research progress in biological targeted therapy for type 2 inflammation in patients with bronchial asthma.https://www.xinyixue.cn/fileup/0253-9802/PDF/1735545799799-688098850.pdfbronchial asthma|type 2 inflammation|biological targeted therapy |
| spellingShingle | ZHANG Mingqiang, MU Xiangdong Biological targeted therapy for type 2 inflammation bronchial asthma Xin yixue bronchial asthma|type 2 inflammation|biological targeted therapy |
| title | Biological targeted therapy for type 2 inflammation bronchial asthma |
| title_full | Biological targeted therapy for type 2 inflammation bronchial asthma |
| title_fullStr | Biological targeted therapy for type 2 inflammation bronchial asthma |
| title_full_unstemmed | Biological targeted therapy for type 2 inflammation bronchial asthma |
| title_short | Biological targeted therapy for type 2 inflammation bronchial asthma |
| title_sort | biological targeted therapy for type 2 inflammation bronchial asthma |
| topic | bronchial asthma|type 2 inflammation|biological targeted therapy |
| url | https://www.xinyixue.cn/fileup/0253-9802/PDF/1735545799799-688098850.pdf |
| work_keys_str_mv | AT zhangmingqiangmuxiangdong biologicaltargetedtherapyfortype2inflammationbronchialasthma |