Synthesis of Novel 7-Phenyl-2,3-Dihydropyrrolo[2,1-<i>b</i>]Quinazolin-9(1<i>H</i>)-ones as Cholinesterase Inhibitors Targeting Alzheimer’s Disease Through Suzuki–Miyaura Cross-Coupling Reaction

Synthesis of Novel 7-Phenyl-2,3-Dihydropyrrolo[2,1-<i>b</i>]Quinazolin-9(1<i>H</i>)-ones as Cholinesterase Inhibitors Targeting Alzheimer’s Disease Through Suzuki–Miyaura Cross-Coupling Reaction

An important field of research in medicinal and organic chemistry involves halogen-containing heterocyclic synthones, which form the backbone of more complex organic compounds. This study aimed to design and synthesize 28 novel derivatives of 7-aryl-2,3-dihydropyrrolo[2,1-<i>b</i>]quinaz...

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Bibliographic Details
Main Authors: Davron Turgunov, Lifei Nie, Azizbek Nasrullaev, Zarifa Murtazaeva, Bianlin Wang, Dilafruz Kholmurodova, Rustamkhon Kuryazov, Jiangyu Zhao, Khurshed Bozorov, Haji Akber Aisa
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
Acetylcholinesterase (AChE)
Alzheimer’s disease
Butyrylcholinesterase (BChE)
carbon–carbon bond (C-C)
deoxyvasicinone
mackinazolinone
Online Access:https://www.mdpi.com/1420-3049/30/13/2791
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