Menopause and rheumatoid arthritis (up to date)

Rheumatoid arthritis (RA) most often affects women, and the onset of RA often occurs around the middle age of menopause. RA in women, compared to men, is more severe, characterized by difficulties in achieving remission and a more negative prognosis. Research results indicate a relationship between...

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Bibliographic Details
Main Authors: T. S. Panevin, A. A. Smetnik, E. G. Zotkin, E. L. Nasonov
Format: Article
Language:Russian
Published: IMA PRESS LLC 2025-07-01
Series:Научно-практическая ревматология
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Online Access:https://rsp.mediar-press.net/rsp/article/view/3764
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Summary:Rheumatoid arthritis (RA) most often affects women, and the onset of RA often occurs around the middle age of menopause. RA in women, compared to men, is more severe, characterized by difficulties in achieving remission and a more negative prognosis. Research results indicate a relationship between menopause, estrogen levels and RA. Early menopause is characterized by an increased risk of developing RA, as well as difficulty achieving remission and a lower quality of life. Menopausal hormone therapy (MHT) may influence both the risk of developing RA and its course. Given the relationship between menopause and other conditions such as obesity, cardiovascular disease, osteoporosis and fibromyalgia, off-label MHT may be one of the possible ways to overcome treatment resistance in RA.
ISSN:1995-4484
1995-4492