High-flow nasal cannula versus non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: a retrospective study

High-flow nasal cannula versus non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: a retrospective study

BackgroundAcute exacerbations of chronic obstructive pulmonary disease (AECOPD) frequently present with acute hypercapnic respiratory failure (AHRF). While non-invasive ventilation (NIV) remains the fist-line therapy, high-flow nasal cannula (HFNC) offers a potential alternative.MethodsThis retrospe...

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Bibliographic Details
Main Authors: Nicolás Colaianni-Alfonso, Ada Toledo, Guillermo Montiel, Cristian Deana, Luigi Vetrugno, Mauro Castro-Sayat
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Medicine
Subjects:
acute hypercapnic respiratory failure
COPD
non-invasive ventilation
high-flow nasal cannula
non-invasive respiratory support (NIRS)
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1582749/full
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