Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.

Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.

Neutralizing antibodies (NAbs) to multiple epitopes on the HIV-1-envelope glycoprotein (Env) have been isolated from infected persons. The potency of NAbs is measured more often than the size of the persistent fraction of infectivity at maximum neutralization, which may also influence preventive eff...

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Main Authors: Rajesh P Ringe, Philippe Colin, Gabriel Ozorowski, Joel D Allen, Anila Yasmeen, Gemma E Seabright, Jeong Hyun Lee, Aleksandar Antanasijevic, Kimmo Rantalainen, Thomas Ketas, John P Moore, Andrew B Ward, Max Crispin, P J Klasse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011601
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