Current principles for the surgical treatment of intrahepatic cholangiocarcinoma
Intrahepatic cholangiocarcinoma is one of the most aggressive forms of cancer. It is usually diagnosed in advanced stages of the disease, mainly because it is asymptomatic for a long time after the onset. Consequently, intrahepatic cholangiocarcinoma still represents an important problem of diagnosi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-10-01
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| Series: | Journal of Mind and Medical Sciences |
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| Online Access: | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1502&context=jmms |
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| author | Catalin Savin Luiza Tarca Irina Balescu Sorin Petrea Bogdan Gaspar Lucian Pop Valentin Varlas Adrian Hasegan Gabriel Petre Gorecki Cristina Martac Marilena Stoian Cristian Balalau Nicolae Bacalbasa |
| author_facet | Catalin Savin Luiza Tarca Irina Balescu Sorin Petrea Bogdan Gaspar Lucian Pop Valentin Varlas Adrian Hasegan Gabriel Petre Gorecki Cristina Martac Marilena Stoian Cristian Balalau Nicolae Bacalbasa |
| author_sort | Catalin Savin |
| collection | DOAJ |
| description | Intrahepatic cholangiocarcinoma is one of the most aggressive forms of cancer. It is usually diagnosed in advanced stages of the disease, mainly because it is asymptomatic for a long time after the onset. Consequently, intrahepatic cholangiocarcinoma still represents an important problem of diagnosis and treatment. In the multidisciplinary treatment of these patients, oncological surgery is essential, as the accuracy of resection is one of the most important prognostic factors for the long-term results of these patients. Therefore, there has been a continuing concern to improve surgical techniques, with the aim of maximizing the chances of achieving the best possible long-term survival. The purpose of this paper is to discuss the surgical standard of care in intrahepatic cholangiocarcinoma, with particular attention being paid to resection margins and lymph node dissection. For unresectable cholangiocarcinoma, locoregional therapy can be used such as transarterial chemoembolization, transarterial radioembolization, thermal ablation, radiotherapy and hepatic artery infusion pump chemotherapy. |
| format | Article |
| id | doaj-art-755669d9f71549719481e8d1244b7913 |
| institution | DOAJ |
| issn | 2392-7674 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Mind and Medical Sciences |
| spelling | doaj-art-755669d9f71549719481e8d1244b79132025-08-20T03:19:17ZengMDPI AGJournal of Mind and Medical Sciences2392-76742024-10-0111232133010.22543/2392-7674.1502Current principles for the surgical treatment of intrahepatic cholangiocarcinomaCatalin Savin0Luiza Tarca1Irina Balescu2Sorin Petrea3Bogdan Gaspar4Lucian Pop5Valentin Varlas6Adrian Hasegan7Gabriel Petre Gorecki8Cristina Martac9Marilena Stoian10Cristian Balalau11Nicolae Bacalbasa12Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaUniversity of Sibiu, Faculty of Medicine, Sibiu Emergency Hospital, Department of Urology, Sibiu, RomaniaTitu Maiorescu University, CF-2 Clinical Hospital, Department of Anesthesia and Intensive Care, Bucharest, RomaniaFundeni Clinical Hospital, Department of Anesthesiology, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, Bucharest, RomaniaIntrahepatic cholangiocarcinoma is one of the most aggressive forms of cancer. It is usually diagnosed in advanced stages of the disease, mainly because it is asymptomatic for a long time after the onset. Consequently, intrahepatic cholangiocarcinoma still represents an important problem of diagnosis and treatment. In the multidisciplinary treatment of these patients, oncological surgery is essential, as the accuracy of resection is one of the most important prognostic factors for the long-term results of these patients. Therefore, there has been a continuing concern to improve surgical techniques, with the aim of maximizing the chances of achieving the best possible long-term survival. The purpose of this paper is to discuss the surgical standard of care in intrahepatic cholangiocarcinoma, with particular attention being paid to resection margins and lymph node dissection. For unresectable cholangiocarcinoma, locoregional therapy can be used such as transarterial chemoembolization, transarterial radioembolization, thermal ablation, radiotherapy and hepatic artery infusion pump chemotherapy.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1502&context=jmmssurgeryintrahepatic cholangiocarcinomaresection marginslymph node dissection |
| spellingShingle | Catalin Savin Luiza Tarca Irina Balescu Sorin Petrea Bogdan Gaspar Lucian Pop Valentin Varlas Adrian Hasegan Gabriel Petre Gorecki Cristina Martac Marilena Stoian Cristian Balalau Nicolae Bacalbasa Current principles for the surgical treatment of intrahepatic cholangiocarcinoma Journal of Mind and Medical Sciences surgery intrahepatic cholangiocarcinoma resection margins lymph node dissection |
| title | Current principles for the surgical treatment of intrahepatic cholangiocarcinoma |
| title_full | Current principles for the surgical treatment of intrahepatic cholangiocarcinoma |
| title_fullStr | Current principles for the surgical treatment of intrahepatic cholangiocarcinoma |
| title_full_unstemmed | Current principles for the surgical treatment of intrahepatic cholangiocarcinoma |
| title_short | Current principles for the surgical treatment of intrahepatic cholangiocarcinoma |
| title_sort | current principles for the surgical treatment of intrahepatic cholangiocarcinoma |
| topic | surgery intrahepatic cholangiocarcinoma resection margins lymph node dissection |
| url | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1502&context=jmms |
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