Factors Influencing Late Breast Toxicity After Radiotherapy: A Scoping Review
Radiation therapy offers well-established benefits in enhancing loco-regional control, distant disease control, and breast-cancer-specific survival. However, it is not without its challenges, particularly in breast cancer patients, where advances in systemic therapies and other treatment modalities...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | BioChem |
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| Online Access: | https://www.mdpi.com/2673-6411/5/2/13 |
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| author | Riccardo Ray Colciago Chiara Chissotti Federica Ferrario Ilenia Manno Matteo Mombelli Giulia Rossano Lorenzo De Sanctis Stefano Arcangeli |
| author_facet | Riccardo Ray Colciago Chiara Chissotti Federica Ferrario Ilenia Manno Matteo Mombelli Giulia Rossano Lorenzo De Sanctis Stefano Arcangeli |
| author_sort | Riccardo Ray Colciago |
| collection | DOAJ |
| description | Radiation therapy offers well-established benefits in enhancing loco-regional control, distant disease control, and breast-cancer-specific survival. However, it is not without its challenges, particularly in breast cancer patients, where advances in systemic therapies and other treatment modalities have significantly improved survival outcomes. As radiation oncologists, our responsibility is to deliver the most effective treatments while minimizing toxicity for each patient. This scoping review aims to retrieve and assess the literature on factors associated with increased radiation-induced late breast toxicity. Specifically, we seek to identify both non-modifiable variables and those that can be influenced by the choices made by radiation oncologists. This review highlights which clinical decisions could directly impact late breast toxicity following adjuvant radiation therapy after breast-conserving surgery. |
| format | Article |
| id | doaj-art-7552ea2895b44fefa3a56e1284b89189 |
| institution | Kabale University |
| issn | 2673-6411 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | BioChem |
| spelling | doaj-art-7552ea2895b44fefa3a56e1284b891892025-08-20T03:26:17ZengMDPI AGBioChem2673-64112025-05-01521310.3390/biochem5020013Factors Influencing Late Breast Toxicity After Radiotherapy: A Scoping ReviewRiccardo Ray Colciago0Chiara Chissotti1Federica Ferrario2Ilenia Manno3Matteo Mombelli4Giulia Rossano5Lorenzo De Sanctis6Stefano Arcangeli7Medicine and Surgery Department, University of Milan Bicocca, 20126 Milano, ItalyRadiation Oncology Unit, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, ItalyRadiation Oncology Unit, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, ItalyMedicine and Surgery Department, University of Milan Bicocca, 20126 Milano, ItalyMedicine and Surgery Department, University of Milan Bicocca, 20126 Milano, ItalyMedicine and Surgery Department, University of Milan Bicocca, 20126 Milano, ItalyMedicine and Surgery Department, University of Milan Bicocca, 20126 Milano, ItalyMedicine and Surgery Department, University of Milan Bicocca, 20126 Milano, ItalyRadiation therapy offers well-established benefits in enhancing loco-regional control, distant disease control, and breast-cancer-specific survival. However, it is not without its challenges, particularly in breast cancer patients, where advances in systemic therapies and other treatment modalities have significantly improved survival outcomes. As radiation oncologists, our responsibility is to deliver the most effective treatments while minimizing toxicity for each patient. This scoping review aims to retrieve and assess the literature on factors associated with increased radiation-induced late breast toxicity. Specifically, we seek to identify both non-modifiable variables and those that can be influenced by the choices made by radiation oncologists. This review highlights which clinical decisions could directly impact late breast toxicity following adjuvant radiation therapy after breast-conserving surgery.https://www.mdpi.com/2673-6411/5/2/13breast cancerradiation therapylate toxicityscoping review |
| spellingShingle | Riccardo Ray Colciago Chiara Chissotti Federica Ferrario Ilenia Manno Matteo Mombelli Giulia Rossano Lorenzo De Sanctis Stefano Arcangeli Factors Influencing Late Breast Toxicity After Radiotherapy: A Scoping Review BioChem breast cancer radiation therapy late toxicity scoping review |
| title | Factors Influencing Late Breast Toxicity After Radiotherapy: A Scoping Review |
| title_full | Factors Influencing Late Breast Toxicity After Radiotherapy: A Scoping Review |
| title_fullStr | Factors Influencing Late Breast Toxicity After Radiotherapy: A Scoping Review |
| title_full_unstemmed | Factors Influencing Late Breast Toxicity After Radiotherapy: A Scoping Review |
| title_short | Factors Influencing Late Breast Toxicity After Radiotherapy: A Scoping Review |
| title_sort | factors influencing late breast toxicity after radiotherapy a scoping review |
| topic | breast cancer radiation therapy late toxicity scoping review |
| url | https://www.mdpi.com/2673-6411/5/2/13 |
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