The Veiled Enigma: Uncovering Subcutaneous Panniculitis-like Cutaneous T-cell Lymphoma

An elderly male patient clinically presented with painful nodules over the trunk which progressed to involve limbs over 2 months. On examination, there were multiple bluish-red subcutaneous nodules with the local rise of the temperature. Clinically, we have considered the following conditions such a...

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Bibliographic Details
Main Authors: Bangaru Hanumaiah, Dhanya Nayak, Sathish Shankar, Pydimukkala Tejaswini Acharya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Clinical Dermatology Review
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Online Access:https://journals.lww.com/10.4103/cdr.cdr_41_24
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Summary:An elderly male patient clinically presented with painful nodules over the trunk which progressed to involve limbs over 2 months. On examination, there were multiple bluish-red subcutaneous nodules with the local rise of the temperature. Clinically, we have considered the following conditions such as lupus panniculitis, erythema nodosum, and other causes for panniculitis. Finally, histopathological examination revealed classical findings suggestive of subcutaneous panniculitis-like T-cell lymphoma which was confirmed by immunohistochemistry. It was a challenging case to diagnose clinically, it needs a high index of suspicion to diagnose early and manage effectively. The patient was started on cyclophosphamide, hydroxyurea, oncovin, and prednisolone therapy.
ISSN:2542-551X
2542-5528