Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications
Emerging per and poly-fluoroalkyl substances (PFASs) are very resistant to degradation and have negative impacts on human and environmental health at very low concentrations. The initial stage in removing PFASs from contaminated locations is their detection and quantification. Particularly utilized...
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| Format: | Article |
| Language: | English |
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AIMS Press
2025-04-01
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| Series: | AIMS Environmental Science |
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| Online Access: | https://www.aimspress.com/article/doi/10.3934/environsci.2025015 |
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| author | Eliasu Issaka Mabruk Adams Enock Adjei Agyekum Josephine Baffoe Blessing Tornyeava |
| author_facet | Eliasu Issaka Mabruk Adams Enock Adjei Agyekum Josephine Baffoe Blessing Tornyeava |
| author_sort | Eliasu Issaka |
| collection | DOAJ |
| description | Emerging per and poly-fluoroalkyl substances (PFASs) are very resistant to degradation and have negative impacts on human and environmental health at very low concentrations. The initial stage in removing PFASs from contaminated locations is their detection and quantification. Particularly utilized in this context are Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS), and High-Performance Liquid Chromatography (HPLC). In this review, we seek to contribute to our understanding of the state-of-the-art in emerging PFAS by offering a complete analysis of PFAS in environments, taking into consideration their sources, classes, and properties. Polyfluoroalkyl ether substances (PFAES), short-chain PFA, replacement PFA, and fluorotelomer-based substances can bioaccumulate in living species, making their detection even more necessary. We intend to provide researchers with an overview of the current state of research on PFASs in environments, encompassing the toxicological effects and their detection and quantification methods, serving as a guide for current and future studies. |
| format | Article |
| id | doaj-art-754d258fe3724ce1b4e1bb0e0d1a5b67 |
| institution | Kabale University |
| issn | 2372-0352 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | AIMS Press |
| record_format | Article |
| series | AIMS Environmental Science |
| spelling | doaj-art-754d258fe3724ce1b4e1bb0e0d1a5b672025-08-20T03:48:19ZengAIMS PressAIMS Environmental Science2372-03522025-04-0112232135110.3934/environsci.2025015Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implicationsEliasu Issaka0Mabruk Adams1Enock Adjei Agyekum2Josephine Baffoe3Blessing Tornyeava4College of Engineering, Birmingham City University, Birmingham B4 7XG, United KingdomCivil Engineering, School of Engineering, College of Science and Engineering, University of Galway, Galway H91TK33, IrelandUltrasound Medical Laboratory, Department of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002 ChinaSchool of Automotive and Traffic Engineering, Jiangsu University, Zhenjiang 212013, P.R. ChinaSchool of Clinical Medicine, Dalian Medical University, Liaoning Province, Dalian 116044, P.R. ChinaEmerging per and poly-fluoroalkyl substances (PFASs) are very resistant to degradation and have negative impacts on human and environmental health at very low concentrations. The initial stage in removing PFASs from contaminated locations is their detection and quantification. Particularly utilized in this context are Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS), and High-Performance Liquid Chromatography (HPLC). In this review, we seek to contribute to our understanding of the state-of-the-art in emerging PFAS by offering a complete analysis of PFAS in environments, taking into consideration their sources, classes, and properties. Polyfluoroalkyl ether substances (PFAES), short-chain PFA, replacement PFA, and fluorotelomer-based substances can bioaccumulate in living species, making their detection even more necessary. We intend to provide researchers with an overview of the current state of research on PFASs in environments, encompassing the toxicological effects and their detection and quantification methods, serving as a guide for current and future studies.https://www.aimspress.com/article/doi/10.3934/environsci.2025015emerging pfaschromatographyspectrometrytoxicological impactsphysicochemical properties |
| spellingShingle | Eliasu Issaka Mabruk Adams Enock Adjei Agyekum Josephine Baffoe Blessing Tornyeava Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications AIMS Environmental Science emerging pfas chromatography spectrometry toxicological impacts physicochemical properties |
| title | Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications |
| title_full | Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications |
| title_fullStr | Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications |
| title_full_unstemmed | Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications |
| title_short | Per- and poly-fluoroalkyl substances: A review of sources, properties, chromatographic detection, and toxicological implications |
| title_sort | per and poly fluoroalkyl substances a review of sources properties chromatographic detection and toxicological implications |
| topic | emerging pfas chromatography spectrometry toxicological impacts physicochemical properties |
| url | https://www.aimspress.com/article/doi/10.3934/environsci.2025015 |
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