Modified Pulsatilla decoction ameliorates ulcerative colitis by affecting gut microbiota and metabolite profiles

Modified Pulsatilla decoction ameliorates ulcerative colitis by affecting gut microbiota and metabolite profiles

To investigate the therapeutic effects of a specific modified Pulsatilla decoction (MPD) on ulcerative colitis (UC) in mice, 32 male Balb/c mice were randomly assigned to four groups: Control, Model, High-dose (H-dose), and Low-dose (L-dose), with eight mice per group. All groups except the Control...

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Bibliographic Details
Main Authors: Zhixin Fu, Xiangyue Xie, Yulei Wang, Zhen Wang, Anran Wu, Shaotang Ye, Yongbo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Microbiology
Subjects:
modified Pulsatilla decoction
ulcerative colitis
16S rRNA sequencing
gut microbiota
metabolomics
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1582559/full
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