Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen
Plasmodium falciparum malaria is the most common infection in Yemen. The present study aims to investigate changes in hematological and hepatic function indices of P. falciparum infected individuals. This study included 67 suspected falciparum malarial patients attended in clinics and rural Abs Hosp...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2016/5954394 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832550079266816000 |
|---|---|
| author | Mohamed Al-Salahy Bushra Shnawa Gamal Abed Ahmed Mandour Ali Al-Ezzi |
| author_facet | Mohamed Al-Salahy Bushra Shnawa Gamal Abed Ahmed Mandour Ali Al-Ezzi |
| author_sort | Mohamed Al-Salahy |
| collection | DOAJ |
| description | Plasmodium falciparum malaria is the most common infection in Yemen. The present study aims to investigate changes in hematological and hepatic function indices of P. falciparum infected individuals. This study included 67 suspected falciparum malarial patients attended in clinics and rural Abs Hospital (Tehama, Hajjah), Yemen, from October 2013 to April 2014. The diagnosis of malaria was confirmed by thick and thin film with Giemsa staining of malaria parasite. Hematological parameters and serum levels of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and bilirubin (total and direct) as test indicators of liver function were studied. Patients with parasitaemia tended to have significantly lower hemoglobin, hematocrit, white blood cell count, lymphocytes, and platelets, compared with healthy normal subjects. Neutrophils levels were significantly higher in cases of falciparum malaria in comparison to healthy normal subjects. Serums AST, ALT, ALP, and bilirubin (total and direct) in falciparum malaria patients were significantly higher (p<0.0001) than those of falciparum malaria of free individuals. Hematological and liver dysfunctions measured parameters were seen associated with moderate and severe parasitaemia infection. This study concludes that hematological and hepatic dysfunction parameters could be indicator of malaria in endemic regions. |
| format | Article |
| id | doaj-art-75445ba3f4cb41e4999ad2df0077e1f2 |
| institution | Kabale University |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-75445ba3f4cb41e4999ad2df0077e1f22025-02-03T06:07:44ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982016-01-01201610.1155/2016/59543945954394Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest YemenMohamed Al-Salahy0Bushra Shnawa1Gamal Abed2Ahmed Mandour3Ali Al-Ezzi4Zoology Department, Faculty of Science, Assiut University, Assiut 71516, EgyptBiology Department, Faculty of Science, Soran University, Kurdistan, IraqZoology Department, Faculty of Science, Assiut University, Assiut 71516, EgyptParasitology Department, Faculty of Medicine, Assiut University, Assiut 71516, EgyptBiology Department, Faculty of Education, Aden University, Aden, YemenPlasmodium falciparum malaria is the most common infection in Yemen. The present study aims to investigate changes in hematological and hepatic function indices of P. falciparum infected individuals. This study included 67 suspected falciparum malarial patients attended in clinics and rural Abs Hospital (Tehama, Hajjah), Yemen, from October 2013 to April 2014. The diagnosis of malaria was confirmed by thick and thin film with Giemsa staining of malaria parasite. Hematological parameters and serum levels of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and bilirubin (total and direct) as test indicators of liver function were studied. Patients with parasitaemia tended to have significantly lower hemoglobin, hematocrit, white blood cell count, lymphocytes, and platelets, compared with healthy normal subjects. Neutrophils levels were significantly higher in cases of falciparum malaria in comparison to healthy normal subjects. Serums AST, ALT, ALP, and bilirubin (total and direct) in falciparum malaria patients were significantly higher (p<0.0001) than those of falciparum malaria of free individuals. Hematological and liver dysfunctions measured parameters were seen associated with moderate and severe parasitaemia infection. This study concludes that hematological and hepatic dysfunction parameters could be indicator of malaria in endemic regions.http://dx.doi.org/10.1155/2016/5954394 |
| spellingShingle | Mohamed Al-Salahy Bushra Shnawa Gamal Abed Ahmed Mandour Ali Al-Ezzi Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen Interdisciplinary Perspectives on Infectious Diseases |
| title | Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen |
| title_full | Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen |
| title_fullStr | Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen |
| title_full_unstemmed | Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen |
| title_short | Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen |
| title_sort | parasitaemia and its relation to hematological parameters and liver function among patients malaria in abs hajjah northwest yemen |
| url | http://dx.doi.org/10.1155/2016/5954394 |
| work_keys_str_mv | AT mohamedalsalahy parasitaemiaanditsrelationtohematologicalparametersandliverfunctionamongpatientsmalariainabshajjahnorthwestyemen AT bushrashnawa parasitaemiaanditsrelationtohematologicalparametersandliverfunctionamongpatientsmalariainabshajjahnorthwestyemen AT gamalabed parasitaemiaanditsrelationtohematologicalparametersandliverfunctionamongpatientsmalariainabshajjahnorthwestyemen AT ahmedmandour parasitaemiaanditsrelationtohematologicalparametersandliverfunctionamongpatientsmalariainabshajjahnorthwestyemen AT alialezzi parasitaemiaanditsrelationtohematologicalparametersandliverfunctionamongpatientsmalariainabshajjahnorthwestyemen |