A bibliometric analysis of exosomes in aging from 2007 to 2023
BackgroundAging is the primary factor contributing to the development of aging-related diseases. As research on exosomes continues to advance, its relationship with aging and aging-related diseases has become a hot topic This article analyzes the research hotspots of exosomes in aging and aging-rela...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1488536/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832591957416738816 |
|---|---|
| author | Zenghui Niu Meiyu Cui Yingkun Fu Lingfeng Zhou Jiali Wang Jiali Wang Yan Lei Xinrong Fan Qiang Wang Jing Yang |
| author_facet | Zenghui Niu Meiyu Cui Yingkun Fu Lingfeng Zhou Jiali Wang Jiali Wang Yan Lei Xinrong Fan Qiang Wang Jing Yang |
| author_sort | Zenghui Niu |
| collection | DOAJ |
| description | BackgroundAging is the primary factor contributing to the development of aging-related diseases. As research on exosomes continues to advance, its relationship with aging and aging-related diseases has become a hot topic This article analyzes the research hotspots of exosomes in aging and aging-related diseases, aiming to fill the gap in bibliometric research in this field and help researchers better understand the current status and future trends of both fundamental and clinical research in this field.MethodsThe articles were retrieved and exported from WoSCC on December 18, 2023. The visual analysis of countries and regions, institutions, authors, references, and keywords in exosomes of aging was conducted using VOSviewer 1.6.18, CiteSpace 6.2.R7, and Bibliometrix.ResultsThe bibliometric analysis included 1628 articles. China and the United States emerged as the top two leading countries in this field. A total of 2,321 research institutions from 78 countries and regions were primarily led by China and the United States. Both Kapogiannis D and Goetzl E were active authors in this field. Thery C, Valadi H, and Raposo G were the important promoters in this field. Thery C proposed the method of differential centrifugation and density gradient centrifugation to extract exosomes. Valadi H discovered cells could send RNA-messages to each other by loading them into exosome-vesicles. The journal with the highest number of articles was International Journal of Molecular Sciences, while PLoS One was the most frequently cited journal. The keyword analysis revealed that future research on exosomes in aging will possibly focus on “inflammation, cellular senescence, angiogenesis, insulin resistance, and Alzheimer's disease.”ConclusionWe identified the research trends of exosomes in the field of aging through this bibliometric analysis. The present study provides valuable new perspectives on the history and current status of exosomes in the field of aging and aging-related diseases, and also offering guidance for future research directions. |
| format | Article |
| id | doaj-art-75437b43c1564bb4b8129127cbbfdb6f |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-75437b43c1564bb4b8129127cbbfdb6f2025-01-22T04:11:52ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011110.3389/fmed.2024.14885361488536A bibliometric analysis of exosomes in aging from 2007 to 2023Zenghui Niu0Meiyu Cui1Yingkun Fu2Lingfeng Zhou3Jiali Wang4Jiali Wang5Yan Lei6Xinrong Fan7Qiang Wang8Jing Yang9Beijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, ChinaBeijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, ChinaGuanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaBeijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, ChinaBeijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, ChinaTianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, ChinaBeijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, ChinaBeijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, ChinaWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaBeijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, ChinaBackgroundAging is the primary factor contributing to the development of aging-related diseases. As research on exosomes continues to advance, its relationship with aging and aging-related diseases has become a hot topic This article analyzes the research hotspots of exosomes in aging and aging-related diseases, aiming to fill the gap in bibliometric research in this field and help researchers better understand the current status and future trends of both fundamental and clinical research in this field.MethodsThe articles were retrieved and exported from WoSCC on December 18, 2023. The visual analysis of countries and regions, institutions, authors, references, and keywords in exosomes of aging was conducted using VOSviewer 1.6.18, CiteSpace 6.2.R7, and Bibliometrix.ResultsThe bibliometric analysis included 1628 articles. China and the United States emerged as the top two leading countries in this field. A total of 2,321 research institutions from 78 countries and regions were primarily led by China and the United States. Both Kapogiannis D and Goetzl E were active authors in this field. Thery C, Valadi H, and Raposo G were the important promoters in this field. Thery C proposed the method of differential centrifugation and density gradient centrifugation to extract exosomes. Valadi H discovered cells could send RNA-messages to each other by loading them into exosome-vesicles. The journal with the highest number of articles was International Journal of Molecular Sciences, while PLoS One was the most frequently cited journal. The keyword analysis revealed that future research on exosomes in aging will possibly focus on “inflammation, cellular senescence, angiogenesis, insulin resistance, and Alzheimer's disease.”ConclusionWe identified the research trends of exosomes in the field of aging through this bibliometric analysis. The present study provides valuable new perspectives on the history and current status of exosomes in the field of aging and aging-related diseases, and also offering guidance for future research directions.https://www.frontiersin.org/articles/10.3389/fmed.2024.1488536/fullbibliometricexosomesagingsenescenceaging-related diseases |
| spellingShingle | Zenghui Niu Meiyu Cui Yingkun Fu Lingfeng Zhou Jiali Wang Jiali Wang Yan Lei Xinrong Fan Qiang Wang Jing Yang A bibliometric analysis of exosomes in aging from 2007 to 2023 Frontiers in Medicine bibliometric exosomes aging senescence aging-related diseases |
| title | A bibliometric analysis of exosomes in aging from 2007 to 2023 |
| title_full | A bibliometric analysis of exosomes in aging from 2007 to 2023 |
| title_fullStr | A bibliometric analysis of exosomes in aging from 2007 to 2023 |
| title_full_unstemmed | A bibliometric analysis of exosomes in aging from 2007 to 2023 |
| title_short | A bibliometric analysis of exosomes in aging from 2007 to 2023 |
| title_sort | bibliometric analysis of exosomes in aging from 2007 to 2023 |
| topic | bibliometric exosomes aging senescence aging-related diseases |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2024.1488536/full |
| work_keys_str_mv | AT zenghuiniu abibliometricanalysisofexosomesinagingfrom2007to2023 AT meiyucui abibliometricanalysisofexosomesinagingfrom2007to2023 AT yingkunfu abibliometricanalysisofexosomesinagingfrom2007to2023 AT lingfengzhou abibliometricanalysisofexosomesinagingfrom2007to2023 AT jialiwang abibliometricanalysisofexosomesinagingfrom2007to2023 AT jialiwang abibliometricanalysisofexosomesinagingfrom2007to2023 AT yanlei abibliometricanalysisofexosomesinagingfrom2007to2023 AT xinrongfan abibliometricanalysisofexosomesinagingfrom2007to2023 AT qiangwang abibliometricanalysisofexosomesinagingfrom2007to2023 AT jingyang abibliometricanalysisofexosomesinagingfrom2007to2023 AT zenghuiniu bibliometricanalysisofexosomesinagingfrom2007to2023 AT meiyucui bibliometricanalysisofexosomesinagingfrom2007to2023 AT yingkunfu bibliometricanalysisofexosomesinagingfrom2007to2023 AT lingfengzhou bibliometricanalysisofexosomesinagingfrom2007to2023 AT jialiwang bibliometricanalysisofexosomesinagingfrom2007to2023 AT jialiwang bibliometricanalysisofexosomesinagingfrom2007to2023 AT yanlei bibliometricanalysisofexosomesinagingfrom2007to2023 AT xinrongfan bibliometricanalysisofexosomesinagingfrom2007to2023 AT qiangwang bibliometricanalysisofexosomesinagingfrom2007to2023 AT jingyang bibliometricanalysisofexosomesinagingfrom2007to2023 |