Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis
Conclusion: Severe CAD demonstrates a shift toward Th2 immunity from Th2/Th1, accompanied by elevated with inflammatory factors such as IL-4, IL-5, IL-31, IL-8, and IFN-γ in skin lesions, as well as increased CD63 exosomes in PB. Thus, consequently, exosomes and Th2/Th1 imbalance may contribute to t...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/mi/7967853 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825199958355083264 |
|---|---|
| author | Tang Jun-Ting Tu Ying Nong Xiang Sun Dong-Jie He Li |
| author_facet | Tang Jun-Ting Tu Ying Nong Xiang Sun Dong-Jie He Li |
| author_sort | Tang Jun-Ting |
| collection | DOAJ |
| description | Conclusion: Severe CAD demonstrates a shift toward Th2 immunity from Th2/Th1, accompanied by elevated with inflammatory factors such as IL-4, IL-5, IL-31, IL-8, and IFN-γ in skin lesions, as well as increased CD63 exosomes in PB. Thus, consequently, exosomes and Th2/Th1 imbalance may contribute to the systemic manifestations observed in CAD patients. |
| format | Article |
| id | doaj-art-75400a5f024b4ea6900c4c9aa90dfbf6 |
| institution | Kabale University |
| issn | 1466-1861 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-75400a5f024b4ea6900c4c9aa90dfbf62025-02-08T00:00:01ZengWileyMediators of Inflammation1466-18612025-01-01202510.1155/mi/7967853Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic DermatitisTang Jun-Ting0Tu Ying1Nong Xiang2Sun Dong-Jie3He Li4Department of Dermatology and VenerologyDepartment of Dermatology and VenerologyDepartment of Dermatology and VenerologyDepartment of Dermatology and VenerologyDepartment of Dermatology and VenerologyConclusion: Severe CAD demonstrates a shift toward Th2 immunity from Th2/Th1, accompanied by elevated with inflammatory factors such as IL-4, IL-5, IL-31, IL-8, and IFN-γ in skin lesions, as well as increased CD63 exosomes in PB. Thus, consequently, exosomes and Th2/Th1 imbalance may contribute to the systemic manifestations observed in CAD patients.http://dx.doi.org/10.1155/mi/7967853 |
| spellingShingle | Tang Jun-Ting Tu Ying Nong Xiang Sun Dong-Jie He Li Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis Mediators of Inflammation |
| title | Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis |
| title_full | Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis |
| title_fullStr | Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis |
| title_full_unstemmed | Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis |
| title_short | Elevated Type 2 Inflammatory Factors, Th2/Th1 Balanced Status, and Exosomes as a Marker of Severity in Chronic Actinic Dermatitis |
| title_sort | elevated type 2 inflammatory factors th2 th1 balanced status and exosomes as a marker of severity in chronic actinic dermatitis |
| url | http://dx.doi.org/10.1155/mi/7967853 |
| work_keys_str_mv | AT tangjunting elevatedtype2inflammatoryfactorsth2th1balancedstatusandexosomesasamarkerofseverityinchronicactinicdermatitis AT tuying elevatedtype2inflammatoryfactorsth2th1balancedstatusandexosomesasamarkerofseverityinchronicactinicdermatitis AT nongxiang elevatedtype2inflammatoryfactorsth2th1balancedstatusandexosomesasamarkerofseverityinchronicactinicdermatitis AT sundongjie elevatedtype2inflammatoryfactorsth2th1balancedstatusandexosomesasamarkerofseverityinchronicactinicdermatitis AT heli elevatedtype2inflammatoryfactorsth2th1balancedstatusandexosomesasamarkerofseverityinchronicactinicdermatitis |