Limited Renal Intravascular Lymphoma: A Case Report and Review of the Literature

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of non-Hodgkin lymphoma. It is characterized by the proliferation of cancerous cells into the intraluminal space of the blood vessels. It has a low incidence rate of 0.095 cases per 1,000,000. The clinical presentation is insidious and u...

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Main Authors: Guillermo Enrique Quintero Vega, Daniel Osorio, José Antonio de la Hoz Valle, Daniela Rodríguez Feria
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2020/7052536
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author Guillermo Enrique Quintero Vega
Daniel Osorio
José Antonio de la Hoz Valle
Daniela Rodríguez Feria
author_facet Guillermo Enrique Quintero Vega
Daniel Osorio
José Antonio de la Hoz Valle
Daniela Rodríguez Feria
author_sort Guillermo Enrique Quintero Vega
collection DOAJ
description Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of non-Hodgkin lymphoma. It is characterized by the proliferation of cancerous cells into the intraluminal space of the blood vessels. It has a low incidence rate of 0.095 cases per 1,000,000. The clinical presentation is insidious and unspecific, often delaying the diagnosis. IVLBCL can be diagnosed through body images and histopathology analysis. This neoplasm averages a 60% response rate to current chemotherapy treatment, favoring rituximab, and doxorubicin-based regimen if it is diagnosed in time. Here, we present the case of a 56-year-old man admitted to our hospital with a fever who was eventually diagnosed with IVLBCL. He presented to the consultation with anemia, fever, and splenomegaly. An infection panel, a bone marrow biopsy, and a PET-CT scan were performed and ruled out the possibility of infections and neoplasms. The patient later developed edematous syndrome. As a result, a renal biopsy was performed which tested positive for intravascular large B-cell lymphoma. Currently, the patient has been in complete remission for 33 months. Along with presenting this specific case, we also reviewed previously published cases of IVLBCL to illustrate the renal involvement of this pathology.
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series Case Reports in Oncological Medicine
spelling doaj-art-7533e449226449bf8fc06c93987b35482025-02-03T06:05:39ZengWileyCase Reports in Oncological Medicine2090-67062090-67142020-01-01202010.1155/2020/70525367052536Limited Renal Intravascular Lymphoma: A Case Report and Review of the LiteratureGuillermo Enrique Quintero Vega0Daniel Osorio1José Antonio de la Hoz Valle2Daniela Rodríguez Feria3Department of Hematology, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, ColombiaDepartment of Hematology, Universidad de los Andes, Bogotá, ColombiaDepartment of Clinical Research, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, ColombiaDepartment of Hematology, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, ColombiaIntravascular large B-cell lymphoma (IVLBCL) is a rare subtype of non-Hodgkin lymphoma. It is characterized by the proliferation of cancerous cells into the intraluminal space of the blood vessels. It has a low incidence rate of 0.095 cases per 1,000,000. The clinical presentation is insidious and unspecific, often delaying the diagnosis. IVLBCL can be diagnosed through body images and histopathology analysis. This neoplasm averages a 60% response rate to current chemotherapy treatment, favoring rituximab, and doxorubicin-based regimen if it is diagnosed in time. Here, we present the case of a 56-year-old man admitted to our hospital with a fever who was eventually diagnosed with IVLBCL. He presented to the consultation with anemia, fever, and splenomegaly. An infection panel, a bone marrow biopsy, and a PET-CT scan were performed and ruled out the possibility of infections and neoplasms. The patient later developed edematous syndrome. As a result, a renal biopsy was performed which tested positive for intravascular large B-cell lymphoma. Currently, the patient has been in complete remission for 33 months. Along with presenting this specific case, we also reviewed previously published cases of IVLBCL to illustrate the renal involvement of this pathology.http://dx.doi.org/10.1155/2020/7052536
spellingShingle Guillermo Enrique Quintero Vega
Daniel Osorio
José Antonio de la Hoz Valle
Daniela Rodríguez Feria
Limited Renal Intravascular Lymphoma: A Case Report and Review of the Literature
Case Reports in Oncological Medicine
title Limited Renal Intravascular Lymphoma: A Case Report and Review of the Literature
title_full Limited Renal Intravascular Lymphoma: A Case Report and Review of the Literature
title_fullStr Limited Renal Intravascular Lymphoma: A Case Report and Review of the Literature
title_full_unstemmed Limited Renal Intravascular Lymphoma: A Case Report and Review of the Literature
title_short Limited Renal Intravascular Lymphoma: A Case Report and Review of the Literature
title_sort limited renal intravascular lymphoma a case report and review of the literature
url http://dx.doi.org/10.1155/2020/7052536
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