Ardisia japonica (Thunb.) Blume and Lespedeza cuneata G. Don may treat chronic obstructive pulmonary disease by targeting HK2 and PTAFR

Ardisia japonica (Thunb.) Blume and Lespedeza cuneata G. Don may treat chronic obstructive pulmonary disease by targeting HK2 and PTAFR

IntroductionPrevious studies have demonstrated the significant efficacy of Ardisia japonica (Thunb.) Blume (Zijinniu) and Lespedeza cuneata G. Don (Tiesaozhou) in alleviating cough and reducing phlegm. This study employed network pharmacology and bioinformatics approaches to identify key genes assoc...

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Bibliographic Details
Main Authors: Xian Luo, Zheng Hang Ge, Shan Luo, Bo Li, Xun Zhou, Yi Yang, Yong Jiang, Tao Tan, Ke Lin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Medicine
Subjects:
chronic obstructive pulmonary disease
active ingredients
network pharmacology
HK2
PTAFR
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1527632/full
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