Swimming Exercise in the Acute or Late Phase after Sciatic Nerve Crush Accelerates Nerve Regeneration
There is no consensus about the best time to start exercise after peripheral nerve injury. We evaluated the morphological and functional characteristics of the sciatic nerves of rats that began to swim immediately after crush nerve injury (CS1), those that began to swim 14 days after injury (CS14),...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2011/783901 |
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| _version_ | 1850221029987713024 |
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| author | Rosana Macher Teodori Joice Betini Larissa Salgado de Oliveira Luciane Lobato Sobral Sibele Yoko Mattozo Takeda Maria Imaculada de Lima Montebelo |
| author_facet | Rosana Macher Teodori Joice Betini Larissa Salgado de Oliveira Luciane Lobato Sobral Sibele Yoko Mattozo Takeda Maria Imaculada de Lima Montebelo |
| author_sort | Rosana Macher Teodori |
| collection | DOAJ |
| description | There is no consensus about the best time to start exercise after peripheral nerve injury. We evaluated the morphological and functional characteristics of the sciatic nerves of rats that began to swim immediately after crush nerve injury (CS1), those that began to swim 14 days after injury (CS14), injured rats not submitted to swimming (C), and uninjured rats submitted to swimming (S). After 30 days the number of axons in CS1 and CS14 was lower than in C (P<0.01). The diameter of axons and nerve fibers was larger in CS1 (P<0.01) and CS14 (P<0.05) than in C, and myelin sheath thickness was lower in all crushed groups (P<0.05). There was no functional difference between CS1 and CS14 (P>0.05). Swimming exercise applied during the acute or late phase of nerve injury accelerated nerve regeneration and synaptic elimination after axonotmesis, suggesting that exercise may be initiated immediately after injury. |
| format | Article |
| id | doaj-art-752e1d5f92204788bfd6d7f5b91ddbda |
| institution | OA Journals |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-752e1d5f92204788bfd6d7f5b91ddbda2025-08-20T02:06:50ZengWileyNeural Plasticity2090-59041687-54432011-01-01201110.1155/2011/783901783901Swimming Exercise in the Acute or Late Phase after Sciatic Nerve Crush Accelerates Nerve RegenerationRosana Macher Teodori0Joice Betini1Larissa Salgado de Oliveira2Luciane Lobato Sobral3Sibele Yoko Mattozo Takeda4Maria Imaculada de Lima Montebelo5Master's Program in Physioterapy, Neuromuscular Plasticity Laboratory, FACIS, Methodist University of Piracicaba, 13400-911 Piracicaba, SP, BrazilFACIS, Universidade Metodista de Piracicaba, 13400-911 Piracicaba, SP, BrazilMaster's Program in Physioterapy, Neuromuscular Plasticity Laboratory, FACIS, Methodist University of Piracicaba, 13400-911 Piracicaba, SP, BrazilMaster's Program in Physioterapy, Neuromuscular Plasticity Laboratory, FACIS, Methodist University of Piracicaba, 13400-911 Piracicaba, SP, BrazilMaster's Program in Physioterapy, Neuromuscular Plasticity Laboratory, FACIS, Methodist University of Piracicaba, 13400-911 Piracicaba, SP, BrazilMaster's Program in Physioterapy, Neuromuscular Plasticity Laboratory, FACIS, Methodist University of Piracicaba, 13400-911 Piracicaba, SP, BrazilThere is no consensus about the best time to start exercise after peripheral nerve injury. We evaluated the morphological and functional characteristics of the sciatic nerves of rats that began to swim immediately after crush nerve injury (CS1), those that began to swim 14 days after injury (CS14), injured rats not submitted to swimming (C), and uninjured rats submitted to swimming (S). After 30 days the number of axons in CS1 and CS14 was lower than in C (P<0.01). The diameter of axons and nerve fibers was larger in CS1 (P<0.01) and CS14 (P<0.05) than in C, and myelin sheath thickness was lower in all crushed groups (P<0.05). There was no functional difference between CS1 and CS14 (P>0.05). Swimming exercise applied during the acute or late phase of nerve injury accelerated nerve regeneration and synaptic elimination after axonotmesis, suggesting that exercise may be initiated immediately after injury.http://dx.doi.org/10.1155/2011/783901 |
| spellingShingle | Rosana Macher Teodori Joice Betini Larissa Salgado de Oliveira Luciane Lobato Sobral Sibele Yoko Mattozo Takeda Maria Imaculada de Lima Montebelo Swimming Exercise in the Acute or Late Phase after Sciatic Nerve Crush Accelerates Nerve Regeneration Neural Plasticity |
| title | Swimming Exercise in the Acute or Late Phase after Sciatic Nerve Crush Accelerates Nerve Regeneration |
| title_full | Swimming Exercise in the Acute or Late Phase after Sciatic Nerve Crush Accelerates Nerve Regeneration |
| title_fullStr | Swimming Exercise in the Acute or Late Phase after Sciatic Nerve Crush Accelerates Nerve Regeneration |
| title_full_unstemmed | Swimming Exercise in the Acute or Late Phase after Sciatic Nerve Crush Accelerates Nerve Regeneration |
| title_short | Swimming Exercise in the Acute or Late Phase after Sciatic Nerve Crush Accelerates Nerve Regeneration |
| title_sort | swimming exercise in the acute or late phase after sciatic nerve crush accelerates nerve regeneration |
| url | http://dx.doi.org/10.1155/2011/783901 |
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