Echinocandin Adaptation in <i>Candida albicans</i> Is Accompanied by Altered Chromatin Accessibility at Gene Promoters and by Cell Wall Remodeling

Echinocandin Adaptation in <i>Candida albicans</i> Is Accompanied by Altered Chromatin Accessibility at Gene Promoters and by Cell Wall Remodeling

Infections by the major opportunistic pathogen of human <i>Candida albicans</i> are commonly treated with echinocandin (ECN) drugs. However, <i>C. albicans</i> can adapt to grow in the presence of certain amounts of ECNs. Prior studies by several laboratories have defined mul...

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Bibliographic Details
Main Authors: Sudisht K. Sah, Anshuman Yadav, Tyler Stahl, Jeffrey J. Hayes, Michael Bulger, Elena Rustchenko
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Journal of Fungi
Subjects:
<i>Candida albicans</i>
ATAC-seq
echinocandin adaptation
Online Access:https://www.mdpi.com/2309-608X/11/2/110
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