Sanren decoction ameliorates ulcerative colitis by modulating gut microbiota and macrophage polarization to enhance intestinal barrier function

Sanren decoction ameliorates ulcerative colitis by modulating gut microbiota and macrophage polarization to enhance intestinal barrier function

Abstract Sanren Decoction (SRD), a traditional Chinese medicine formula historically used to relieve damp-heat and gastrointestinal disorders, demonstrates targeted efficacy in ulcerative colitis (UC)—a disease marked by chronic inflammation and mucosal damage—by acting on multiple pathological path...

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Bibliographic Details
Main Authors: Shujuan Zhang, BangHua Li, Xiaoqun Han, LinLin Ruan, Xingxing Fu, Yanglin Chen, Hongtao Wan, Xiaojian Zhu, Dan Liu, Bo Yi
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Chinese Medicine
Subjects:
Sanren decoction
Ulcerative colitis
Gut microbiota
PTGS2
Macrophage polarization
Microbial dysbiosis
Online Access:https://doi.org/10.1186/s13020-025-01183-1
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