Determination of the Corrosion and Biocompatibility Properties of As-Cast TiNi Alloys

In this study, a TiNi alloy with a composition of 50 at.% of titanium and 50 at.% of nickel is investigated in terms of its corrosion and biocompatibility behavior for biomedical applications. The corrosion measurements, which include the determination of open-circuit potential and linear polarizati...

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Main Authors: Minja Miličić Lazić, Dijana Mitić, Biljana Dojčinović, Marko Lazić, Aleksandra S. Popović, Branimir N. Grgur
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Metals
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Online Access:https://www.mdpi.com/2075-4701/15/7/758
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author Minja Miličić Lazić
Dijana Mitić
Biljana Dojčinović
Marko Lazić
Aleksandra S. Popović
Branimir N. Grgur
author_facet Minja Miličić Lazić
Dijana Mitić
Biljana Dojčinović
Marko Lazić
Aleksandra S. Popović
Branimir N. Grgur
author_sort Minja Miličić Lazić
collection DOAJ
description In this study, a TiNi alloy with a composition of 50 at.% of titanium and 50 at.% of nickel is investigated in terms of its corrosion and biocompatibility behavior for biomedical applications. The corrosion measurements, which include the determination of open-circuit potential and linear polarization resistance measurements, cyclic polarization measurements, and electrochemical impedance spectroscopy in 9 g L<sup>−1</sup> NaCl, show that TiNi has satisfactory corrosion stability. According to the SEM and EDS analysis, after cyclic polarization, pitting corrosion occurred, accompanied by the dissolution of the unstable Ti<sub>2</sub>Ni inclusions. The analysis also showed that TiNi has good biocompatibility for human osteoblast-like cells, as determined by the mitochondrial activity, which was assessed using a direct contact test following ISO standard 10993-5, via scanning electron microscopy (SEM) and fluorescent microscopy.
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issn 2075-4701
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publishDate 2025-07-01
publisher MDPI AG
record_format Article
series Metals
spelling doaj-art-75172b8f6bcf49f99a7bed2c3816d8ea2025-08-20T03:08:13ZengMDPI AGMetals2075-47012025-07-0115775810.3390/met15070758Determination of the Corrosion and Biocompatibility Properties of As-Cast TiNi AlloysMinja Miličić Lazić0Dijana Mitić1Biljana Dojčinović2Marko Lazić3Aleksandra S. Popović4Branimir N. Grgur5Faculty of Dental Medicine, University of Belgrade, Dr Subotica 8, 11000 Belgrade, SerbiaFaculty of Dental Medicine, University of Belgrade, Dr Subotica 8, 11000 Belgrade, SerbiaInstitute of Chemistry, Technology and Metallurgy (ICTM), National Institute of the Republic of Serbia, University of Belgrade, Njegoševa 12, 11000 Belgrade, SerbiaFaculty of Dental Medicine, University of Belgrade, Dr Subotica 8, 11000 Belgrade, SerbiaFaculty of Technology and Metallurgy, University of Belgrade, 11200, Belgrade, SerbiaFaculty of Technology and Metallurgy, University of Belgrade, 11200, Belgrade, SerbiaIn this study, a TiNi alloy with a composition of 50 at.% of titanium and 50 at.% of nickel is investigated in terms of its corrosion and biocompatibility behavior for biomedical applications. The corrosion measurements, which include the determination of open-circuit potential and linear polarization resistance measurements, cyclic polarization measurements, and electrochemical impedance spectroscopy in 9 g L<sup>−1</sup> NaCl, show that TiNi has satisfactory corrosion stability. According to the SEM and EDS analysis, after cyclic polarization, pitting corrosion occurred, accompanied by the dissolution of the unstable Ti<sub>2</sub>Ni inclusions. The analysis also showed that TiNi has good biocompatibility for human osteoblast-like cells, as determined by the mitochondrial activity, which was assessed using a direct contact test following ISO standard 10993-5, via scanning electron microscopy (SEM) and fluorescent microscopy.https://www.mdpi.com/2075-4701/15/7/758open-circuit potentialcyclic polarizationimpedanceTi<sub>2</sub>Niosteoblast cells
spellingShingle Minja Miličić Lazić
Dijana Mitić
Biljana Dojčinović
Marko Lazić
Aleksandra S. Popović
Branimir N. Grgur
Determination of the Corrosion and Biocompatibility Properties of As-Cast TiNi Alloys
Metals
open-circuit potential
cyclic polarization
impedance
Ti<sub>2</sub>Ni
osteoblast cells
title Determination of the Corrosion and Biocompatibility Properties of As-Cast TiNi Alloys
title_full Determination of the Corrosion and Biocompatibility Properties of As-Cast TiNi Alloys
title_fullStr Determination of the Corrosion and Biocompatibility Properties of As-Cast TiNi Alloys
title_full_unstemmed Determination of the Corrosion and Biocompatibility Properties of As-Cast TiNi Alloys
title_short Determination of the Corrosion and Biocompatibility Properties of As-Cast TiNi Alloys
title_sort determination of the corrosion and biocompatibility properties of as cast tini alloys
topic open-circuit potential
cyclic polarization
impedance
Ti<sub>2</sub>Ni
osteoblast cells
url https://www.mdpi.com/2075-4701/15/7/758
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