Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine
Background/Aim. Surgical extraction of lower third molars is followed by mild or severe postoperative pain which peaks at maximal intensity in the first 12 hours and has a significant impact on a patient’s postoperative quality of life. The use of long-acting local anaesthetics is a promisi...
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| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2015-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501501050B.pdf |
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| author | Brajković Denis Biočanin Vladimir Milić Marija Vučetić Milan Petrović Renata Brković Božidar |
| author_facet | Brajković Denis Biočanin Vladimir Milić Marija Vučetić Milan Petrović Renata Brković Božidar |
| author_sort | Brajković Denis |
| collection | DOAJ |
| description | Background/Aim. Surgical extraction of lower third molars is followed by mild
or severe postoperative pain which peaks at maximal intensity in the first 12
hours and has a significant impact on a patient’s postoperative quality of
life. The use of long-acting local anaesthetics is a promising strategy to
improve postoperative analgesia. The aim of the present study was to
investigate analgesic parameters and patient satisfaction after using 0.5%
levobupivacaine (Lbup), 0.5% bupivacaine (Bup) and 2% lidocaine with
epinephrine 1:80,000 (Lid + Epi) for an inferior alveolar nerve block
following lower third molar surgery. Methods. A total of 102 patients (ASA I)
were divided into three groups, each of which received either 3 mL of Lbup,
Bup or Lid + Epi. The intensity of postoperative analgesia was measured using
a verbal rating scale (VRS). The total amounts of rescue analgesics were
recorded on the first and during seven postoperative days. Patients
satisfaction was noted using a modified verbal scales. Results. A
significantly higher level of postoperative pain was recorded in Lid + Epi
group compared to Bup and Lbup groups. No significant differences were seen
between Bup and Lbup, but a significant reduction in the need for rescue
analgesics was seen postoperatively in both Lbup and Bup (50%) in comparison
with Lid + Epi (80%) in the first 24 hours. The same significant trend in
rescue analgesic consumption was recorded for seven postoperative days.
Patients’ overall satisfaction was significantly lower for Lid + Epi (10%)
than for Lbup (56%) and Bup (52%). Conclusion. The use of a new and
long-acting local anaesthetic 0.5% levobupivacaine is clinically relevant and
effective for an inferior alveolar nerve block and postoperative pain control
after third molar surgery. In our study Lbup and Bup controled postoperative
pain more efficiently after lower third molar surgery compared to Lid + Epi.
[Projekat Ministarstva nauke Republike Srbije, br. 175021] |
| format | Article |
| id | doaj-art-751306ef2a5f48de82c6055a75d0f4d5 |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-751306ef2a5f48de82c6055a75d0f4d52025-08-20T03:19:14ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502015-01-01721505610.2298/VSP1501050B0042-84501501050BQuality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrineBrajković Denis0Biočanin Vladimir1Milić Marija2Vučetić Milan3Petrović Renata4Brković Božidar5Faculty of Medicine, Department of Maxillofacial Surgery, KragujevacFaculty of Medicine, Department of Oral Surgery, KragujevacFaculty of Dental Medicine, Clinic of Oral Surgery, BelgradeFaculty of Dental Medicine, Clinic of Oral Surgery, BelgradeFaculty of Dental Medicine, Department of Restorative Dentistry and Endodontics, BelgradeFaculty of Dental Medicine, Clinic of Oral Surgery, BelgradeBackground/Aim. Surgical extraction of lower third molars is followed by mild or severe postoperative pain which peaks at maximal intensity in the first 12 hours and has a significant impact on a patient’s postoperative quality of life. The use of long-acting local anaesthetics is a promising strategy to improve postoperative analgesia. The aim of the present study was to investigate analgesic parameters and patient satisfaction after using 0.5% levobupivacaine (Lbup), 0.5% bupivacaine (Bup) and 2% lidocaine with epinephrine 1:80,000 (Lid + Epi) for an inferior alveolar nerve block following lower third molar surgery. Methods. A total of 102 patients (ASA I) were divided into three groups, each of which received either 3 mL of Lbup, Bup or Lid + Epi. The intensity of postoperative analgesia was measured using a verbal rating scale (VRS). The total amounts of rescue analgesics were recorded on the first and during seven postoperative days. Patients satisfaction was noted using a modified verbal scales. Results. A significantly higher level of postoperative pain was recorded in Lid + Epi group compared to Bup and Lbup groups. No significant differences were seen between Bup and Lbup, but a significant reduction in the need for rescue analgesics was seen postoperatively in both Lbup and Bup (50%) in comparison with Lid + Epi (80%) in the first 24 hours. The same significant trend in rescue analgesic consumption was recorded for seven postoperative days. Patients’ overall satisfaction was significantly lower for Lid + Epi (10%) than for Lbup (56%) and Bup (52%). Conclusion. The use of a new and long-acting local anaesthetic 0.5% levobupivacaine is clinically relevant and effective for an inferior alveolar nerve block and postoperative pain control after third molar surgery. In our study Lbup and Bup controled postoperative pain more efficiently after lower third molar surgery compared to Lid + Epi. [Projekat Ministarstva nauke Republike Srbije, br. 175021]http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501501050B.pdftooth extractionmolar, thirdbupivacainelidocaineanesthesia, dentalpain, postoperativequestionaires |
| spellingShingle | Brajković Denis Biočanin Vladimir Milić Marija Vučetić Milan Petrović Renata Brković Božidar Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine Vojnosanitetski Pregled tooth extraction molar, third bupivacaine lidocaine anesthesia, dental pain, postoperative questionaires |
| title | Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine |
| title_full | Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine |
| title_fullStr | Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine |
| title_full_unstemmed | Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine |
| title_short | Quality of analgesia after lower third molar surgery: A randomised, double-blind study of levobupivacaine, bupivacaine and lidocaine with epinephrine |
| title_sort | quality of analgesia after lower third molar surgery a randomised double blind study of levobupivacaine bupivacaine and lidocaine with epinephrine |
| topic | tooth extraction molar, third bupivacaine lidocaine anesthesia, dental pain, postoperative questionaires |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501501050B.pdf |
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