Effectiveness of Activated Charcoal Toothpaste vs. 6% Hydrogen Peroxide Whitening Pen—An In Vitro Study
<b>Background:</b> Tooth whitening is a widely sought-after cosmetic procedure, with various at-home and professional treatments available. This study compares the whitening efficacy of an activated charcoal toothpaste and a 6% hydrogen peroxide whitening pen under controlled in vitro co...
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MDPI AG
2025-05-01
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| author | Elena Bardellini Silvia Marchetti Alessandra Bordanzi Simone Zanini Alessandra Majorana Giulio Conti |
| author_facet | Elena Bardellini Silvia Marchetti Alessandra Bordanzi Simone Zanini Alessandra Majorana Giulio Conti |
| author_sort | Elena Bardellini |
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| description | <b>Background:</b> Tooth whitening is a widely sought-after cosmetic procedure, with various at-home and professional treatments available. This study compares the whitening efficacy of an activated charcoal toothpaste and a 6% hydrogen peroxide whitening pen under controlled in vitro conditions. <b>Methods:</b> Twenty freshly extracted human teeth were stained with a coffee solution and divided into two groups. Group A underwent daily applications of activated charcoal toothpaste for 30 days, while Group B received a single 5 min application of a 6% hydrogen peroxide whitening pen. Tooth color was assessed using the VITA Classical A1-D4 Shade Guide at baseline, mid-treatment, and post-treatment for Group A and at baseline and immediately after treatment for Group B. <b>Results:</b> The activated charcoal toothpaste exhibited a gradual whitening effect, with the most significant improvements occurring within the first two weeks (<i>p</i> < 0.01), after which the whitening effect plateaued. In contrast, the hydrogen peroxide whitening pen produced immediate and substantial whitening (<i>p</i> < 0.001). Statistical analysis using the Wilcoxon signed-rank test and Mann–Whitney U test confirmed the superior efficacy of the hydrogen peroxide treatment. <b>Conclusions:</b> The hydrogen peroxide whitening pen was significantly more effective in achieving rapid and substantial whitening compared to the activated charcoal toothpaste, which provided gradual but limited improvements. Further clinical studies are needed to evaluate the long-term color stability. |
| format | Article |
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| institution | OA Journals |
| issn | 2304-6767 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
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| series | Dentistry Journal |
| spelling | doaj-art-750d167f3fce4497ac8f67b6f970b4f42025-08-20T02:33:44ZengMDPI AGDentistry Journal2304-67672025-05-0113521610.3390/dj13050216Effectiveness of Activated Charcoal Toothpaste vs. 6% Hydrogen Peroxide Whitening Pen—An In Vitro StudyElena Bardellini0Silvia Marchetti1Alessandra Bordanzi2Simone Zanini3Alessandra Majorana4Giulio Conti5Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, School of Dentistry, University of Brescia, 25123 Brescia, ItalyDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, School of Dentistry, University of Brescia, 25123 Brescia, ItalyDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, School of Dentistry, University of Brescia, 25123 Brescia, ItalyDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, School of Dentistry, University of Brescia, 25123 Brescia, ItalyDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, School of Dentistry, University of Brescia, 25123 Brescia, ItalyHead and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37129 Verona, Italy<b>Background:</b> Tooth whitening is a widely sought-after cosmetic procedure, with various at-home and professional treatments available. This study compares the whitening efficacy of an activated charcoal toothpaste and a 6% hydrogen peroxide whitening pen under controlled in vitro conditions. <b>Methods:</b> Twenty freshly extracted human teeth were stained with a coffee solution and divided into two groups. Group A underwent daily applications of activated charcoal toothpaste for 30 days, while Group B received a single 5 min application of a 6% hydrogen peroxide whitening pen. Tooth color was assessed using the VITA Classical A1-D4 Shade Guide at baseline, mid-treatment, and post-treatment for Group A and at baseline and immediately after treatment for Group B. <b>Results:</b> The activated charcoal toothpaste exhibited a gradual whitening effect, with the most significant improvements occurring within the first two weeks (<i>p</i> < 0.01), after which the whitening effect plateaued. In contrast, the hydrogen peroxide whitening pen produced immediate and substantial whitening (<i>p</i> < 0.001). Statistical analysis using the Wilcoxon signed-rank test and Mann–Whitney U test confirmed the superior efficacy of the hydrogen peroxide treatment. <b>Conclusions:</b> The hydrogen peroxide whitening pen was significantly more effective in achieving rapid and substantial whitening compared to the activated charcoal toothpaste, which provided gradual but limited improvements. Further clinical studies are needed to evaluate the long-term color stability.https://www.mdpi.com/2304-6767/13/5/216tooth whiteninghydrogen peroxideactivated charcoal toothpaste |
| spellingShingle | Elena Bardellini Silvia Marchetti Alessandra Bordanzi Simone Zanini Alessandra Majorana Giulio Conti Effectiveness of Activated Charcoal Toothpaste vs. 6% Hydrogen Peroxide Whitening Pen—An In Vitro Study Dentistry Journal tooth whitening hydrogen peroxide activated charcoal toothpaste |
| title | Effectiveness of Activated Charcoal Toothpaste vs. 6% Hydrogen Peroxide Whitening Pen—An In Vitro Study |
| title_full | Effectiveness of Activated Charcoal Toothpaste vs. 6% Hydrogen Peroxide Whitening Pen—An In Vitro Study |
| title_fullStr | Effectiveness of Activated Charcoal Toothpaste vs. 6% Hydrogen Peroxide Whitening Pen—An In Vitro Study |
| title_full_unstemmed | Effectiveness of Activated Charcoal Toothpaste vs. 6% Hydrogen Peroxide Whitening Pen—An In Vitro Study |
| title_short | Effectiveness of Activated Charcoal Toothpaste vs. 6% Hydrogen Peroxide Whitening Pen—An In Vitro Study |
| title_sort | effectiveness of activated charcoal toothpaste vs 6 hydrogen peroxide whitening pen an in vitro study |
| topic | tooth whitening hydrogen peroxide activated charcoal toothpaste |
| url | https://www.mdpi.com/2304-6767/13/5/216 |
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