Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1.

Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1.

The β-glucan receptor Dectin-1 is a member of the C-type lectin family and functions as an innate pattern recognition receptor in antifungal immunity. In both mouse and man, Dectin-1 has been found to play an essential role in controlling infections with Candida albicans, a normally commensal fungus...

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Main Authors: Mohlopheni J Marakalala, Simon Vautier, Joanna Potrykus, Louise A Walker, Kelly M Shepardson, Alex Hopke, Hector M Mora-Montes, Ann Kerrigan, Mihai G Netea, Graeme I Murray, Donna M Maccallum, Robert Wheeler, Carol A Munro, Neil A R Gow, Robert A Cramer, Alistair J P Brown, Gordon D Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003315&type=printable
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