Neisseria Gonorrhoeae Spontaneous Bacterial Peritonitis

We describe a case of gonococcal spontaneous bacterial peritonitis (SBP) in a 48-year-old sexually active female with alcoholic cirrhosis and chronic hepatitis B. She was admitted with fever, abdominal pain and distension without dysuria, dyspareunia, or vaginal discharge. On exam, she was icteric w...

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Main Authors: George Mwandia, Ryan Q. Simon, Hari Polenakovik, Katelyn J. Booher
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2021/8865339
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author George Mwandia
Ryan Q. Simon
Hari Polenakovik
Katelyn J. Booher
author_facet George Mwandia
Ryan Q. Simon
Hari Polenakovik
Katelyn J. Booher
author_sort George Mwandia
collection DOAJ
description We describe a case of gonococcal spontaneous bacterial peritonitis (SBP) in a 48-year-old sexually active female with alcoholic cirrhosis and chronic hepatitis B. She was admitted with fever, abdominal pain and distension without dysuria, dyspareunia, or vaginal discharge. On exam, she was icteric with features of sepsis and tense ascites. She underwent paracentesis. The ascitic fluid analysis revealed a neutrophil count of 1,050/µL, and culture grew Neisseria gonorrhoeae. Pelvic examination findings were negative for pelvic inflammatory disease; however, an endocervical swab was positive for N. gonorrhoeae by PCR. She was diagnosed with spontaneous bacterial peritonitis secondary to N. gonorrhoeae and was successfully treated with a seven-day course of IV ceftriaxone. N. gonorrhoeae spontaneous bacterial peritonitis is an extremely rare entity reported only twice despite the high prevalence of gonorrhoeae in the general population. We hypothesize that gonococcal SBP may be frequently undiagnosed since it responds to empiric antibiotics used to treat SBP. It is important for the clinician to be aware of gonococcus as a rare but potential pathogen in SBP. Future studies are needed to determine if routine gonococcal screening in SBP cases would be of clinical utility.
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spelling doaj-art-74ffd7d50d20442ea72b3af33822ba312025-02-03T01:09:56ZengWileyCase Reports in Infectious Diseases2090-66252090-66332021-01-01202110.1155/2021/88653398865339Neisseria Gonorrhoeae Spontaneous Bacterial PeritonitisGeorge Mwandia0Ryan Q. Simon1Hari Polenakovik2Katelyn J. Booher3Wright State University Boonshoft School of Medicine, Department of Infectious Diseases, Weber CHE Building, 2nd Floor E Apple St. Dayton, Dayton, OH 45409-2902, USAWright State University Boonshoft School of Medicine, Department of Infectious Diseases, Weber CHE Building, 2nd Floor E Apple St. Dayton, Dayton, OH 45409-2902, USAWright State University Boonshoft School of Medicine, Department of Infectious Diseases, Weber CHE Building, 2nd Floor E Apple St. Dayton, Dayton, OH 45409-2902, USAWright State University Boonshoft School of Medicine, Department of Infectious Diseases, Weber CHE Building, 2nd Floor E Apple St. Dayton, Dayton, OH 45409-2902, USAWe describe a case of gonococcal spontaneous bacterial peritonitis (SBP) in a 48-year-old sexually active female with alcoholic cirrhosis and chronic hepatitis B. She was admitted with fever, abdominal pain and distension without dysuria, dyspareunia, or vaginal discharge. On exam, she was icteric with features of sepsis and tense ascites. She underwent paracentesis. The ascitic fluid analysis revealed a neutrophil count of 1,050/µL, and culture grew Neisseria gonorrhoeae. Pelvic examination findings were negative for pelvic inflammatory disease; however, an endocervical swab was positive for N. gonorrhoeae by PCR. She was diagnosed with spontaneous bacterial peritonitis secondary to N. gonorrhoeae and was successfully treated with a seven-day course of IV ceftriaxone. N. gonorrhoeae spontaneous bacterial peritonitis is an extremely rare entity reported only twice despite the high prevalence of gonorrhoeae in the general population. We hypothesize that gonococcal SBP may be frequently undiagnosed since it responds to empiric antibiotics used to treat SBP. It is important for the clinician to be aware of gonococcus as a rare but potential pathogen in SBP. Future studies are needed to determine if routine gonococcal screening in SBP cases would be of clinical utility.http://dx.doi.org/10.1155/2021/8865339
spellingShingle George Mwandia
Ryan Q. Simon
Hari Polenakovik
Katelyn J. Booher
Neisseria Gonorrhoeae Spontaneous Bacterial Peritonitis
Case Reports in Infectious Diseases
title Neisseria Gonorrhoeae Spontaneous Bacterial Peritonitis
title_full Neisseria Gonorrhoeae Spontaneous Bacterial Peritonitis
title_fullStr Neisseria Gonorrhoeae Spontaneous Bacterial Peritonitis
title_full_unstemmed Neisseria Gonorrhoeae Spontaneous Bacterial Peritonitis
title_short Neisseria Gonorrhoeae Spontaneous Bacterial Peritonitis
title_sort neisseria gonorrhoeae spontaneous bacterial peritonitis
url http://dx.doi.org/10.1155/2021/8865339
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AT haripolenakovik neisseriagonorrhoeaespontaneousbacterialperitonitis
AT katelynjbooher neisseriagonorrhoeaespontaneousbacterialperitonitis