PET/MRI is superior to PET/CT in detecting oesophago and gastric carcinomas: a meta-analysis

Abstract Objectives To compare the accuracy rates of the detection and staging of oesophago and gastric carcinomas between PET/MRI and PET/CT. Methods An extensive librarian-led literature search of PubMed, Embase, Web of Science, the Cochrane Central Library, and CNKI was performed and a meta-analy...

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Main Authors: Bo Peng, Hui Sun, Jian Hou, Jian-Xing Luo
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cancer Imaging
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Online Access:https://doi.org/10.1186/s40644-025-00871-3
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Summary:Abstract Objectives To compare the accuracy rates of the detection and staging of oesophago and gastric carcinomas between PET/MRI and PET/CT. Methods An extensive librarian-led literature search of PubMed, Embase, Web of Science, the Cochrane Central Library, and CNKI was performed and a meta-analysis was done. Results Six studies, including 123 participants, were analyzed. PET/MRI had a comparatively high sensitivity in primary lesion detection compared with PET/CT. (RR = 1.14, 95% CI 1.01–1.29, P = 0.036).PET/MRI had no significant statistical differences in all aspects of TNM staging compared with PET/CT. Conclusions This systematic review confirmed the advantage of PET/MRI in detecting oesophago and gastric carcinomas.Compared with PET/CT, it can reduce unnecessary radiation exposure and can be used in relevant patients without contraindications of MRI.
ISSN:1470-7330