Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa
Background. COVID-19 has been a major public health concern globally, leading to a higher mortality rate, especially among immunosuppressed individuals, who include pregnant women, people with HIV and people living with other comorbidities. Pregnant women are considered to be a special populati...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
South African Medical Association
2024-03-01
|
| Series: | South African Medical Journal |
| Subjects: | |
| Online Access: | https://samajournals.co.za/index.php/samj/article/view/702 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823860577327382528 |
|---|---|
| author | I Rukasha S T S Pheeha M R Lekalakala P Malope |
| author_facet | I Rukasha S T S Pheeha M R Lekalakala P Malope |
| author_sort | I Rukasha |
| collection | DOAJ |
| description |
Background. COVID-19 has been a major public health concern globally, leading to a higher mortality rate, especially among immunosuppressed individuals, who include pregnant women, people with HIV and people living with other comorbidities. Pregnant women are considered to be a special population group owing to their specific susceptibility to some infectious diseases.
Objective. To determine the seroprevalence of anti-SARS-CoV-2 antibodies among pregnant women attending an antenatal clinic. Method. This was a descriptive cross-sectional study that tested blood samples from pregnant women who attended the antenatal clinic from March to July 2022 using the Orient Gene Biotech lateral flow immune-chromatographic assay according to manufacturer instructions. The assay detects IgM and IgG antibodies against SARS-CoV-2.
Results. A total of 2 649 blood samples were tested; 2 039 (77.0%) samples tested positive for IgG, 7 (0.3%) tested positive for IgM, and 100 (3.7%) tested positive for both IgG and IgM. The study found a seroprevalence of 80.7% of IgG.
Conclusion. The study findings showed evidence of acute COVID-19 infection in our patient population despite the consensus that COVID-19 infection is dissipating.
|
| format | Article |
| id | doaj-art-74eb37bbc94c42aea30428df79ba72b9 |
| institution | Kabale University |
| issn | 0256-9574 2078-5135 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | South African Medical Association |
| record_format | Article |
| series | South African Medical Journal |
| spelling | doaj-art-74eb37bbc94c42aea30428df79ba72b92025-02-10T12:26:24ZengSouth African Medical AssociationSouth African Medical Journal0256-95742078-51352024-03-01114310.7196/SAMJ.2024.v114i3.702Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South AfricaI Rukasha0S T S Pheeha1M R Lekalakala2P Malope3Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Limpopo, South Africa; Department of Medical Microbiology, National Health Laboratory Services, Polokwane, South AfricaDivision of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Limpopo, South Africa; Department of Haematology, National Health Laboratory Services, Polokwane, South AfricaDivision of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Limpopo, South Africa; Department of Medical Microbiology, National Health Laboratory Services, Polokwane, South AfricaDivision of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Limpopo, South Africa Background. COVID-19 has been a major public health concern globally, leading to a higher mortality rate, especially among immunosuppressed individuals, who include pregnant women, people with HIV and people living with other comorbidities. Pregnant women are considered to be a special population group owing to their specific susceptibility to some infectious diseases. Objective. To determine the seroprevalence of anti-SARS-CoV-2 antibodies among pregnant women attending an antenatal clinic. Method. This was a descriptive cross-sectional study that tested blood samples from pregnant women who attended the antenatal clinic from March to July 2022 using the Orient Gene Biotech lateral flow immune-chromatographic assay according to manufacturer instructions. The assay detects IgM and IgG antibodies against SARS-CoV-2. Results. A total of 2 649 blood samples were tested; 2 039 (77.0%) samples tested positive for IgG, 7 (0.3%) tested positive for IgM, and 100 (3.7%) tested positive for both IgG and IgM. The study found a seroprevalence of 80.7% of IgG. Conclusion. The study findings showed evidence of acute COVID-19 infection in our patient population despite the consensus that COVID-19 infection is dissipating. https://samajournals.co.za/index.php/samj/article/view/702COVID-19, Seroprevalence, pregnant women, Immunoglobulin |
| spellingShingle | I Rukasha S T S Pheeha M R Lekalakala P Malope Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa South African Medical Journal COVID-19, Seroprevalence, pregnant women, Immunoglobulin |
| title | Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa |
| title_full | Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa |
| title_fullStr | Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa |
| title_full_unstemmed | Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa |
| title_short | Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa |
| title_sort | determination of anti covid 19 igg and igm seroprevalence among pregnant women at pietersburg hospital limpopo province south africa |
| topic | COVID-19, Seroprevalence, pregnant women, Immunoglobulin |
| url | https://samajournals.co.za/index.php/samj/article/view/702 |
| work_keys_str_mv | AT irukasha determinationofanticovid19iggandigmseroprevalenceamongpregnantwomenatpietersburghospitallimpopoprovincesouthafrica AT stspheeha determinationofanticovid19iggandigmseroprevalenceamongpregnantwomenatpietersburghospitallimpopoprovincesouthafrica AT mrlekalakala determinationofanticovid19iggandigmseroprevalenceamongpregnantwomenatpietersburghospitallimpopoprovincesouthafrica AT pmalope determinationofanticovid19iggandigmseroprevalenceamongpregnantwomenatpietersburghospitallimpopoprovincesouthafrica |