Inflammatory Myofibroblastic Tumor of the Nasal Septum
We report an extremely rare case of inflammatory myofibroblastic tumor of the posterior edge of the nasal septum. An 11-year-old boy presented with frequent epistaxis and nasal obstruction persisting for one year. Based on the clinical presentation and imaging studies, juvenile angiofibroma was susp...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2013/670105 |
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| author | Yuri Okumura Kazuhiro Nomura Takeshi Oshima Atsuko Kasajima Takahiro Suzuki Eichi Ishida Toshimitsu Kobayashi |
| author_facet | Yuri Okumura Kazuhiro Nomura Takeshi Oshima Atsuko Kasajima Takahiro Suzuki Eichi Ishida Toshimitsu Kobayashi |
| author_sort | Yuri Okumura |
| collection | DOAJ |
| description | We report an extremely rare case of inflammatory myofibroblastic tumor of the posterior edge of the nasal septum. An 11-year-old boy presented with frequent epistaxis and nasal obstruction persisting for one year. Based on the clinical presentation and imaging studies, juvenile angiofibroma was suspected, but angiography suggested the possibility of another type of tumor. Transnasal endoscopic surgery found that the tumor protruded into the nasopharynx from the posterior end of the nasal septum. Histological examination identified spindle cells with immunoreaction for vimentin, smooth muscle actin, and anaplastic lymphoma kinase (ALK), but not for desmin and cytokeratin. This is a report of inflammatory myofibroblastic tumor mimicking juvenile angiofibroma. This case suggests that angiography is helpful in the differential diagnosis of epipharyngeal tumor in adolescence. |
| format | Article |
| id | doaj-art-74ea3f506e5f490da840763af7b8d911 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-74ea3f506e5f490da840763af7b8d9112025-02-03T06:48:37ZengWileyCase Reports in Otolaryngology2090-67652090-67732013-01-01201310.1155/2013/670105670105Inflammatory Myofibroblastic Tumor of the Nasal SeptumYuri Okumura0Kazuhiro Nomura1Takeshi Oshima2Atsuko Kasajima3Takahiro Suzuki4Eichi Ishida5Toshimitsu Kobayashi6Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Pathology, Tohoku University Hospital, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, JapanDepartment of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, JapanWe report an extremely rare case of inflammatory myofibroblastic tumor of the posterior edge of the nasal septum. An 11-year-old boy presented with frequent epistaxis and nasal obstruction persisting for one year. Based on the clinical presentation and imaging studies, juvenile angiofibroma was suspected, but angiography suggested the possibility of another type of tumor. Transnasal endoscopic surgery found that the tumor protruded into the nasopharynx from the posterior end of the nasal septum. Histological examination identified spindle cells with immunoreaction for vimentin, smooth muscle actin, and anaplastic lymphoma kinase (ALK), but not for desmin and cytokeratin. This is a report of inflammatory myofibroblastic tumor mimicking juvenile angiofibroma. This case suggests that angiography is helpful in the differential diagnosis of epipharyngeal tumor in adolescence.http://dx.doi.org/10.1155/2013/670105 |
| spellingShingle | Yuri Okumura Kazuhiro Nomura Takeshi Oshima Atsuko Kasajima Takahiro Suzuki Eichi Ishida Toshimitsu Kobayashi Inflammatory Myofibroblastic Tumor of the Nasal Septum Case Reports in Otolaryngology |
| title | Inflammatory Myofibroblastic Tumor of the Nasal Septum |
| title_full | Inflammatory Myofibroblastic Tumor of the Nasal Septum |
| title_fullStr | Inflammatory Myofibroblastic Tumor of the Nasal Septum |
| title_full_unstemmed | Inflammatory Myofibroblastic Tumor of the Nasal Septum |
| title_short | Inflammatory Myofibroblastic Tumor of the Nasal Septum |
| title_sort | inflammatory myofibroblastic tumor of the nasal septum |
| url | http://dx.doi.org/10.1155/2013/670105 |
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