82 Leveraging the biodesign process to create impactful medical technologies: A study in neurosurgery
Objectives/Goals: This study demonstrates the utility of the CBID biodesign process for identifying and prioritizing high-impact neurosurgical needs. The research emphasizes the process’s role in developing innovative medical technologies that align with the healthcare ecosystem’s demands and stakeh...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2025-04-01
|
| Series: | Journal of Clinical and Translational Science |
| Online Access: | https://www.cambridge.org/core/product/identifier/S205986612400760X/type/journal_article |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850097801359261696 |
|---|---|
| author | Arjun Menta Arjun K. Menta Ava Taylor Kenny Nova Sofia Garcia del Barrio Cervera Shreya Jindal Anders Sideris William S. Anderson Soumyadipta Acharya Youseph Yazdi |
| author_facet | Arjun Menta Arjun K. Menta Ava Taylor Kenny Nova Sofia Garcia del Barrio Cervera Shreya Jindal Anders Sideris William S. Anderson Soumyadipta Acharya Youseph Yazdi |
| author_sort | Arjun Menta |
| collection | DOAJ |
| description | Objectives/Goals: This study demonstrates the utility of the CBID biodesign process for identifying and prioritizing high-impact neurosurgical needs. The research emphasizes the process’s role in developing innovative medical technologies that align with the healthcare ecosystem’s demands and stakeholder priorities. Methods/Study Population: The CBID Spiral Innovation Model, integrating clinical, technical, business, and strategic considerations across clinical challenges in neurosurgery was employed over a 15-week period at a tertiary care center. The process involved three phases: (1) needs identification through 8 weeks of clinical immersion, (2) 7–8 weeks of stakeholder engagement via informational interviews, surveys, and conferences, and (3) iterative refinement based on evidence generation and market value. Stakeholders included over 70 clinicians (neurosurgeons, neurocritical care specialists, neurologists, etc.) across 15 institutions as well as more than 10 payers and hospital administrators. Data collection encompassed direct observation, structured interviews, and comprehensive literature review. Results/Anticipated Results: The initial list of 300+ identified neurosurgical needs was reduced to 271 after clinician and market input. High-level market and clinical evidence assessments further reduced this to 74 needs. Finally, through iterative evaluation of evidence generation, market opportunity, and stakeholder feedback, five critical unmet needs in stroke, traumatic brain injury, hydrocephalus, and epilepsy were identified for technological innovation. These needs met the criteria for clinical importance, economic viability, and market accessibility. The findings highlight the effectiveness of the biodesign process in creating a roadmap for innovation that is both clinically relevant and commercially viable. Discussion/Significance of Impact: This study underscores the effectiveness of structured need-finding and prioritization within neurosurgery. Integrating stakeholder perspectives and rigorous analysis, it provides a replicable framework for medical innovation to accelerate the development of impactful solutions across medicine. |
| format | Article |
| id | doaj-art-74e414cefc474a2f99adafe465296c60 |
| institution | DOAJ |
| issn | 2059-8661 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj-art-74e414cefc474a2f99adafe465296c602025-08-20T02:40:52ZengCambridge University PressJournal of Clinical and Translational Science2059-86612025-04-019262610.1017/cts.2024.76082 Leveraging the biodesign process to create impactful medical technologies: A study in neurosurgeryArjun Menta0Arjun K. Menta1Ava Taylor2Kenny Nova3Sofia Garcia del Barrio Cervera4Shreya Jindal5Anders Sideris6William S. Anderson7Soumyadipta Acharya8Youseph Yazdi9Johns Hopkins School of MedicineDepartment of Neurosurgery, Johns Hopkins University School of Medicine Baltimore Center for Bioengineering Innovation & Design (CBID) Whiting School of Engineering, Johns Hopkins University, BaltimoreCenter for Bioengineering Innovation & Design (CBID) Whiting School of Engineering, Johns Hopkins University, BaltimoreCenter for Bioengineering Innovation & Design (CBID) Whiting School of Engineering, Johns Hopkins University, BaltimoreCenter for Bioengineering Innovation & Design (CBID) Whiting School of Engineering, Johns Hopkins University, BaltimoreCenter for Bioengineering Innovation & Design (CBID) Whiting School of Engineering, Johns Hopkins University, BaltimoreCenter for Bioengineering Innovation & Design (CBID) Whiting School of Engineering, Johns Hopkins University, BaltimoreDepartment of Neurosurgery, Johns Hopkins University School of Medicine BaltimoreCenter for Bioengineering Innovation & Design (CBID) Whiting School of Engineering, Johns Hopkins University, BaltimoreCenter for Bioengineering Innovation & Design (CBID) Whiting School of Engineering, Johns Hopkins University, BaltimoreObjectives/Goals: This study demonstrates the utility of the CBID biodesign process for identifying and prioritizing high-impact neurosurgical needs. The research emphasizes the process’s role in developing innovative medical technologies that align with the healthcare ecosystem’s demands and stakeholder priorities. Methods/Study Population: The CBID Spiral Innovation Model, integrating clinical, technical, business, and strategic considerations across clinical challenges in neurosurgery was employed over a 15-week period at a tertiary care center. The process involved three phases: (1) needs identification through 8 weeks of clinical immersion, (2) 7–8 weeks of stakeholder engagement via informational interviews, surveys, and conferences, and (3) iterative refinement based on evidence generation and market value. Stakeholders included over 70 clinicians (neurosurgeons, neurocritical care specialists, neurologists, etc.) across 15 institutions as well as more than 10 payers and hospital administrators. Data collection encompassed direct observation, structured interviews, and comprehensive literature review. Results/Anticipated Results: The initial list of 300+ identified neurosurgical needs was reduced to 271 after clinician and market input. High-level market and clinical evidence assessments further reduced this to 74 needs. Finally, through iterative evaluation of evidence generation, market opportunity, and stakeholder feedback, five critical unmet needs in stroke, traumatic brain injury, hydrocephalus, and epilepsy were identified for technological innovation. These needs met the criteria for clinical importance, economic viability, and market accessibility. The findings highlight the effectiveness of the biodesign process in creating a roadmap for innovation that is both clinically relevant and commercially viable. Discussion/Significance of Impact: This study underscores the effectiveness of structured need-finding and prioritization within neurosurgery. Integrating stakeholder perspectives and rigorous analysis, it provides a replicable framework for medical innovation to accelerate the development of impactful solutions across medicine.https://www.cambridge.org/core/product/identifier/S205986612400760X/type/journal_article |
| spellingShingle | Arjun Menta Arjun K. Menta Ava Taylor Kenny Nova Sofia Garcia del Barrio Cervera Shreya Jindal Anders Sideris William S. Anderson Soumyadipta Acharya Youseph Yazdi 82 Leveraging the biodesign process to create impactful medical technologies: A study in neurosurgery Journal of Clinical and Translational Science |
| title | 82 Leveraging the biodesign process to create impactful medical technologies: A study in neurosurgery |
| title_full | 82 Leveraging the biodesign process to create impactful medical technologies: A study in neurosurgery |
| title_fullStr | 82 Leveraging the biodesign process to create impactful medical technologies: A study in neurosurgery |
| title_full_unstemmed | 82 Leveraging the biodesign process to create impactful medical technologies: A study in neurosurgery |
| title_short | 82 Leveraging the biodesign process to create impactful medical technologies: A study in neurosurgery |
| title_sort | 82 leveraging the biodesign process to create impactful medical technologies a study in neurosurgery |
| url | https://www.cambridge.org/core/product/identifier/S205986612400760X/type/journal_article |
| work_keys_str_mv | AT arjunmenta 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT arjunkmenta 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT avataylor 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT kennynova 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT sofiagarciadelbarriocervera 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT shreyajindal 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT anderssideris 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT williamsanderson 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT soumyadiptaacharya 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery AT yousephyazdi 82leveragingthebiodesignprocesstocreateimpactfulmedicaltechnologiesastudyinneurosurgery |